Results 181 to 190 of about 29,895 (257)

AlphaFold2‐Guided Cyclic Peptide Stabilizer Design to Target Protein–Protein Interactions

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The control and modulation of protein–protein interactions (PPIs) is of central importance for the majority of biological processes and most biomedical applications. Stabilization of PPIs, besides inhibition, is of growing pharmaceutical interest.
Niklas Halbwedl, Martin Zacharias
wiley   +1 more source

Bioinformatics‐Driven Design and Evaluation of Recombinant Multi‐Epitope Immunogens Derived From Snake Venom Toxins as Potential Antivenom Candidates

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Snakebite envenomation is a major public health concern, particularly in low‐ and middle‐income regions where access to safe and effective antivenoms is limited. Traditional antivenoms, derived from immunization with crude venom, often trigger adverse reactions and lack specificity against key venom components.
Hanan Maoz, Amir Elalouf
wiley   +1 more source

On univalent functions. I. [PDF]

open access: yesČasopis pro pěstování matematiky, 1967
openaire   +2 more sources

Leveraging Electrochemical Diversity in Engineering Liquid‐State Ionic Devices for Neuromorphic Computing

open access: yesSmall, EarlyView.
Mixed‐ion transport through Å‐scale pores exhibits various functions, including voltage activation, voltage inactivation, nanopulse generation, and synaptic behavior. Our work reveals that one of the fundamental advantages of ionic computing over electronic computingthe diversity of charge carriersdirectly translates into functional diversity in the ...
Yechan Noh, Alex Smolyanitsky
wiley   +1 more source

High Sensitivity Cardiac Troponin I Detection via MP‐Locked Aptamer and Multimeric DNAzyme‐Coupled Hyperbranched Hybridization Chain Reaction

open access: yesSmall, EarlyView.
We report a magnetic particle anchored locked aptamer platform integrated with hyperbranched HCR and DNAzyme amplification for enzyme‐free, ultrasensitive detection of cardiac troponin I. The assay achieves a 0.25 ng/L detection limit within 25 minutes and enables cross‐species MI detection, with machine learning classification reaching 90% accuracy ...
Sayantan Tripathy   +9 more
wiley   +1 more source

Acid Resistant and Highly Silver Selective Membranes Based on Charged Nanoporous 2D‐Materials

open access: yesSmall, EarlyView.
In this work, new membranes based on charged & nanoporous nanosheets with unprecedented selectivity to silver versus a wide range of other metallic ions are reported. Furthermore, a demonstrated and lead specific intralamellar lead pathway is demonstrated. A potential applicability for ubiquitous silver in WEEE is validated.
Sarah M. Chevrier   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy