Results 21 to 30 of about 28,174 (201)
Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley +1 more source
The Univalence Principle is the statement that equivalent mathematical structures are indistinguishable. We prove a general version of this principle that applies to all set-based, categorical, and higher-categorical structures defined in a non-algebraic and space-based style, as well as models of higher-order theories such as topological spaces.
Ahrens, Benedikt+3 more
openaire +3 more sources
ON UNIVALENCE OF INTEGRAL OPERATORS [PDF]
In this paper we consider functions of psi(lambda) and we define integral operators denoted by F-beta,F-lambda and G(beta,lambda) using by psi(lambda), then we proved sufficient conditions for univalence of these integral operators.
openaire +4 more sources
Molecular dynamics simulations are advancing the study of ribonucleic acid (RNA) and RNA‐conjugated molecules. These developments include improvements in force fields, long‐timescale dynamics, and coarse‐grained models, addressing limitations and refining methods.
Kanchan Yadav, Iksoo Jang, Jong Bum Lee
wiley +1 more source
Tin‐Based 2D/3D Perovskite Vertical Heterojunction for High‐Performance Synaptic Phototransistors
Phototransistors based on tin‐based 2D/3D perovskite heterostructures show an ultrahigh responsivity and detectivity at a low gate voltage across a broad wavelength region from ultraviolet to near‐infrared. The devices can replicate neuromorphic learning and remembering behaviors to light stimuli, in addition to electric depression and memory erasure ...
Hok‐Leung Loi+10 more
wiley +1 more source
A lack of standard approaches for testing and reporting the performance of metal halide perovskites and organic semiconductor radiation detectors has resulted in inconsistent interpretation of performance parameters, impeding progress in the field. This Perspective recommends key metrics and experimental details, which are suggested for reporting in ...
Jessie A. Posar+8 more
wiley +1 more source
Structuralism, Invariance, and Univalence [PDF]
The recent discovery of an interpretation of constructive type theory into abstract homotopy theory suggests a new approach to the foundations of mathematics with intrinsic geometric content and a computational implementation. Voevodsky has proposed such a program, including a new axiom with both geometric and logical significance: the Univalence Axiom.
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Faradaic charging with bromine redox chemistry shows promise for energy storage, yet its efficient use in aqueous electrolytes is hindered by water decomposition and polybromides' cross‐diffusion, leading to suboptimal cell performance. This study introduces a tetrabutylammonium bromide‐based hydrated deep eutectic electrolyte with optimized water ...
Tae Pyeong Eom+4 more
wiley +1 more source
Univalent categories constitute a well-behaved and useful notion of category in univalent foundations. The notion of univalence has subsequently been generalized to bicategories and other structures in (higher) category theory. Here, we zoom in on monoidal categories and study them in a univalent setting.
Wullaert, Kobe+2 more
openaire +5 more sources
Product of univalent functions [PDF]
Abstract Let S denote the class of functions f analytic and univalent in the unit disk | z | 1 normalized such that f ( 0 ) = 0 = f ′ ( 0 ) − 1 . In this article the authors discuss the radius of univalence of F ( z ) = g ( z ) h ( z ) / z when g and h belong ...
Obradović, Milutin+1 more
openaire +1 more source