Results 161 to 170 of about 3,901 (215)

Enzymatic synthesis of bioactive quinolones and (thio)coumarins by fungal type III polyketide synthases

The FEBS Journal, EarlyView.
Quinolones are valuable scaffolds for drug discovery but are rare in nature. Here, we show that two fungal enzymes, AthePKS and FerePKS, can generate 2‐quinolones and two additional heteroaromatic scaffolds. Using AthePKS, we designed an artificial enzymatic cascade towards an antimicrobial quinolone from a simple precursor and implemented it in E ...
Nika Sokolova, Angelina Osipyan, Lili Zhang, Matthew R. Groves, Sandy Schmidt, Kristina Haslinger   +5 more
wiley   +1 more source

Bioinspired twist-hyperbolic metamaterial for impact buffering and self-powered real-time sensing in UAVs. [PDF]

Sci Adv
Chao X, Hu H, Lin J, Ge X, Wang Y, Xie L, Hu B, Meng L, Yu S, Liang F, Qi L, Wang ZL.   +11 more
europepmc   +1 more source

Deciphering the properties and reaction mechanism of anhydromevalonate phosphate decarboxylase, a prenylated flavin mononucleotide‐dependent enzyme in the archaeal mevalonate pathway

The FEBS Journal, EarlyView.
Characterization of anhydromevalonate phosphate decarboxylase, the UbiD‐family decarboxylase involved in the archaeal mevalonate pathway, was conducted. The enzyme is responsible for the biosynthesis of isoprenoids, such as archaeal membrane lipids, respiratory quinones, and dolichols.
Rino Ishikawa, Natsumi Matsushima, Soma Ishimine, Honoka Nakamoto, Hajime Hayakawa, Yoko Yasuno, Tetsuro Shinada, Hiroshi Kawaide, Tomokazu Ito, Hisashi Hemmi   +9 more
wiley   +1 more source

Image edge detection enhancement using coefficients of Sakaguchi type functions mapped onto petal shaped domain. [PDF]

Heliyon
Nithiyanandham EK, Srutha Keerthi B.
europepmc   +1 more source

Are We Conflating Innovation Resistance With Innovation (Non‐)Adoption? A Reflection and Potential Resolution

Journal of Product Innovation Management, EarlyView.
ABSTRACT Academic Summary In the realm of innovation studies, examining innovation responses—encompassing both adoption and resistance—has been a central focus for more than six decades. However, most innovation studies only focus on the behavioral dimension of these responses and simply equate resistance with non‐adoption.
Juliëtte van Acker, Bas Hillebrand, Simone M. Ritter, Mark A. Wiering, Rob W. Holland   +4 more
wiley   +1 more source

Local and global control adjustments to stimulus-based task conflict in task switching. [PDF]

Q J Exp Psychol (Hove)
Moretti L, Koch I, Schuch S.
europepmc   +1 more source

The Loewner Energy via the Renormalised Energy of Moving Frames. [PDF]

Arch Ration Mech Anal
Michelat A, Wang Y.
europepmc   +1 more source

S100PBP interacts with nucleoporin TPR and facilitates XY crossover formation in mice. [PDF]

EMBO Rep
Wu Y, Li Y, Zhang H, Ye J, Li M, Zhou J, Xie X, Yin H, Chen M, Yang G, Fan S, Shi B, Jiang H, Shi Q, Ma H.   +14 more
europepmc   +1 more source

Coefficient bounds for starlike functions involving q- Hurwitz-Lerch Zeta operator in conic region. [PDF]

Heliyon
Uma K, Vijaya K.
europepmc   +1 more source

Multi-Talented Bismuthinidenes: Double C(sp³)─I Bond Activation Using Single or Two Bi Centers. [PDF]

Chemistry
Novák P, Hejda M, Jambor R, Růžička A, Gagnon A, Dostál L.   +5 more
europepmc   +1 more source