Results 101 to 110 of about 2,827,055 (299)

Molecular Glue Degraders Enhance CAPRIN1‐Dependent Lysosomal Degradation of APP and Reduce Amyloid β in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
A new class of lysosome‐directed molecular glue degraders selectively enhance CAPRIN1–APP interactions, driving APP degradation and reducing amyloid‐β production in human neurons and Alzheimer's disease mouse models. This CAPRIN1‐dependent targeted protein degradation strategy reveals a previously unrecognized therapeutic approach for disrupting the ...
Sunghan Jung   +15 more
wiley   +1 more source

Some Subordination Theorems of Univalent Functions Defined by Linear Operators

open access: yes, 2016
[[abstract]]In this paper we study some applications of the theory of differential subordination defined on the space of univalent functions which are defined by linear operators.
M. E. Drbuk, R. M. EL-Ashwah
core  

Univalent functions with univalent derivatives [PDF]

open access: yesBulletin of the American Mathematical Society, 1969
Shah, S. M., Trimble, S. Y.
openaire   +2 more sources

An ATP‐Driven N Protein–DDX21 Molecular Switch Dynamically Controls SARS‐CoV‐2 RNA G‐Quadruplex Heterogeneity

open access: yesAdvanced Science, EarlyView.
An ATP‐driven molecular switch, comprising viral nucleocapsid (N) protein and host helicase DDX21, dynamically modulates SARS‐CoV‐2 RNA G‐quadruplex (G4) heterogeneity. These viral G4s feature non‐canonical ion‐dependence and act as energy‐sensitive structural checkpoints.
Ya‐Ting Zheng   +8 more
wiley   +1 more source

Extremal properties of extreme and support points of univalent functions with montel normalization

open access: yes, 2008
Let U = {z : vertical bar z vertical bar < 1} be the unit disk. The Montel class, M(a), is the class of functions f (z) = a(1)z + a(2)z(2) +..., which are analytic and univalent in the unit disk and satisfy the conditions f (0) = 0 and f (a) = a, (0 ...
UÇAR, FARUK
core   +1 more source

A Versatile DNA‐Encoded Library Platform for the Discovery of Highly Cooperative Chemical Inducers of Proximity

open access: yesAdvanced Science, EarlyView.
We present a versatile DNA‐encoded library (DEL) platform designed for rapid library synthesis and subsequent screening for chemical inducers of proximity (CIPs) across various presenter proteins of choice. Applying this approach, we discovered a novel molecular glue‐like compound mediating CRBN‐BRD9 ternary complex formation with remarkable ...
Bingqi Tong   +11 more
wiley   +1 more source

Subclasses of univalent functions subordinate to convex functions [PDF]

open access: yes, 1997
In this paper, we define a new subclass ℳα(A,B) of univalent functions and investigate several interesting characterization theorems involving a general class S*A,B of starlike ...
Il Bong Jung, Yong Chan Kim
core   +2 more sources

Oral Recombinant Human Collagen III Protects Gastric Mucosa via G‐Quadruplex‐Mediated Activation of the Pla2g4a‐Prostaglandin Axis

open access: yesAdvanced Science, EarlyView.
Orally administered recombinant human type III collagen protects the gastric mucosa from ethanol‐induced injury by coordinating redox homeostasis, epithelial barrier repair, and arachidonic acid–prostaglandin metabolism. Gastric digestion releases the pentapeptide GPAEF, which interacts with the Pla2g4a promoter G‐quadruplex in a structure‐dependent ...
Xinyue Lan   +14 more
wiley   +1 more source

A new class of Salagean-type harmonic univalent functions

open access: yes, 2005
We define and investigate a new class of Salagean-type harmonic univalent functions. We obtain coefficient conditions, extreme points, distortion bounds, convex combination and radii of convex for the above class of harmonic univalent ...

core   +1 more source

On the Coefficients of Univalent Functions [PDF]

open access: yesJournal of the London Mathematical Society, 1967
Clunie, J., Pommerenke, Ch.
openaire   +4 more sources

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