Results 121 to 130 of about 10,555,595 (364)

Discovery of SKP2‐Recruiting PROTACs for Target Protein Degradation

Advanced Science, EarlyView.
Based on the SKP2‐targeting ligand SL1, we designed non‐covalent PROTACs by linking it with the BRD4 inhibitor JQ1 and the AR antagonist AL through a linker. These PROTACs successfully induced the ubiquitination of BRD4 and AR, followed by proteasome‐mediated degradation.
Guanjun Dong, Aima Huang, Ziqing Zhao, Bikai Lai, Xin Pan, Huiyu Yang, Xiaohan Xu, Tianwei Wang, Fangchen Zhao, Zhimin Zhang, Yongbo Xue, Guanjun Deng, Wenbin Deng, Jianwei Chen   +13 more
wiley   +1 more source

On certain analytic univalent functions

International Journal of Mathematics and Mathematical Sciences, 2001
We consider the class of analytic functions B(α) to investigate some properties for this class. The angular estimates of functions in the class B(α) are obtained.
B. A. Frasin, M. Darus
doaj   +1 more source

Harmonic functions with varying coefficients

Journal of Inequalities and Applications, 2016
Complex-valued harmonic functions that are univalent and sense preserving in the open unit disk can be written in the form f = h + g ‾ $f=h+\overline{g}$ , where h and g are analytic.
Jacek Dziok, Jay Jahangiri, Herb Silverman   +2 more
doaj   +1 more source

Osmotic Tension Asymmetry Drives Electrotactic Migration via PDLIM7‐Polarized Microfilament Coordination in Breast Cancer Cells

Advanced Science, EarlyView.
This study establishes an electric field‐induced directional migration model using fluorescence tension probes to visualize microfilament forces and intracellular osmotic pressure dynamics in the electrotactic migration of breast cancer cells. This model delineates how electromechanical interactions among membrane potential, ion channels, OP, traction ...
Ling Zhu, Zihui Zheng, Wang Li, Chenyi Shou, Ying Zhao, Lijun Zhang, Xiaoli Shi, Yunfeng Hu, Huanhuan Zhao, Huiwen Wu, Jun Guo   +10 more
wiley   +1 more source

DNA Nanoflower LYTACs Enable Efficient VEGF Degradation and Verteporfin Loading for Combined Therapy of Wet Age‐Related Macular Degeneration

Advanced Science, EarlyView.
An integrated approach that combines a DNA nanoflower VEGF degrader with photodynamic therapy is developed for the treatment of wet age‐related macular degeneration, which reduces the risk of VEGF reactivation‐induced CNV recurrence and minimizes the systemic side effects associated with photodynamic therapy.
Mengxuan Li, Yan Yue, Sijin Wu, Xinyu He, Jiayi Song, Shuwen Ma, Haokun Zhang, Chenyu Xu, Song Chen, Yanming Huang, Songbo Xie, Hua Yan   +11 more
wiley   +1 more source

Construction of Planar Harmonic Functions

International Journal of Mathematics and Mathematical Sciences, 2007
Complex-valued harmonic functions that are univalent and sense-preserving in the open unit disk can be written in the form f=h+g¯, where h and g are analytic in the open unit disk.
Jay M. Jahangiri, Herb Silverman, Evelyn M. Silvia   +2 more
doaj   +1 more source

Univalent Functions with Univalent Derivatives. II [PDF]

Transactions of the American Mathematical Society, 1969
Shah, S. M., Trimble, S. Y.
openaire   +3 more sources

Univalent functions with univalent sections [PDF]

, 1998
Contains fulltext : 265336.pdf (Publisher’s version ) (Open Access)
openaire  

DNA‐Guided Robust Single‐Protein Electronic Readout

Advanced Science, EarlyView.
Electronic measurements of single proteins can reveal fundamental insights into their structure, dynamics, and interactions, but reproducibility is severely limited by the intrinsic structural heterogeneity of proteins combined with uncontrolled molecular orientation and electrode contact geometries.
Ziyi Ju, Zhaoxiang Deng, Yueqi Li, Jinghong Li   +3 more
wiley   +1 more source

On some classes of analytic functions

International Journal of Mathematics and Mathematical Sciences, 1987
Let m1, m2 be any numbers and let Vm1,m2 be the class of functions of analytic in the unit disc E={z:|z|
Khalida I. Noor, Haila Madifer
doaj   +1 more source