Results 161 to 170 of about 635,609 (243)

FOXC1 as a molecular predictor of postoperative peritumoral edema resolution in meningiomas. [PDF]

J Neurooncol
Basaran AE, Braune M, Barrantes-Freer A, Müller WC, Vychopen M, Güresir E, Wach J.   +6 more
europepmc   +1 more source

Metal Active‐Site Exposure via Ligand Engineering Boosts CO2‐to‐Ethylene Conversion on Cu18 Nanoclusters

Advanced Science, EarlyView.
Through quantitative ligand stripping of [Cu18H17(PR3)10]+ nanoclusters via intramolecular interaction modulation, selectivity for CO2 electroreduction to C2H4 is significantly enhanced. The weakly coordinating ligand triggers dual‐ligand stripping (FEC2H4 = 70.59%), whereas the strongly coordinating ligand results in single‐ligand retention (FEC2H4 ...
Ziqi Chen, Yang Zuo, Yu Zhu, Shuo Zhang, Along Ma, Shiyin Yang, Zhengmao Yin, Xiaoshuang Ma, Shuxin Wang   +8 more
wiley   +1 more source

Implant failure and postoperative complications after stabilization surgery for spinal metastases: A single-center cohort study. [PDF]

Brain Spine
Thavarajasingam SG, Salih A, Brühl C, Scurtu D, Kanakala S, Namireddy S, Ramsay D, Thavarajasingam A, Beutel TM, Neuhoff J, Pollok J, Turgut M, Jankovic D, Ringel F, Kramer A.   +14 more
europepmc   +1 more source

Tumor‐Derived Exosomal circAP2B1 Induces M2 Macrophage Polarization by Enhancing Mitochondrial Homeostasis to Promote Esophageal Squamous Cell Carcinoma Progression

Advanced Science, EarlyView.
ESCC‐derived exosomal circAP2B1 promotes tumor progression by reprogramming mitochondrial metabolism via the ESRRA/KPNA1/MFN2 axis to induce M2 polarization of macrophages. ABSTRACT Esophageal squamous cell carcinoma (ESCC) remodels the immunosuppressive tumor microenvironment via exosome‐mediated intercellular communication.
Yiru Wang, Gang Feng, Youyu Wang, Ruihao Liang, Haixia Pan, Kai Lei   +5 more
wiley   +1 more source

A Coupled Inflammatory-Fibrotic-Nitrosative Axis in Patients with Patent Foramen Ovale and Cryptogenic Stroke. [PDF]

J Clin Med
Tworek M, Trojanowicz K, Sachajko Z, Kowalik-Pandyra M, Pacia K, Bielecka K, Szczepara S, Tworek M, Natorska J, Kopeć G, Komar M.   +10 more
europepmc   +1 more source

TSTScope Unifies Single‐Cell Multi‐Omics to Identify Functional T Cell States Predictive of Immunotherapy Response

Advanced Science, EarlyView.
TSTScope is an interpretable AI framework that integrates single‐cell transcriptomes with TCR information through curated gene‐program constraints. By linking receptor context to functional T cell states, it reveals response‐associated tumor‐specific T cell programs in lung cancer immunotherapy cohorts and defines an MPR score associated with ...
Shiwei Cao, Jinyu Cheng, Feng‐ao Wang, Chenxin Yi, Jiajun Chen, Keyue Wang, Lulu Liu, Junwei Liu, Yixue Li   +8 more
wiley   +1 more source

Cardiovascular Comorbidities and Advanced Chronic Kidney Disease in Hospitalized Patients with Multiple Myeloma: A Single-Center Retrospective Cohort Study. [PDF]

Diseases
Bălăceanu LA, Tiron AT, Baboi ID, Iacobescu CG, Bălăceanu-Gurău B, Gurău CD, Grigorescu IV, Dina I.   +7 more
europepmc   +1 more source

circZNF148 Drives Glucose Metabolism Reprogramming to Enhance Metastasis and Immune Evasion via HK1 Stabilization in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
CircZNF148 stabilizes HK1 through deubiquitinase recruitment, thereby enhancing glycolysis and lactate production. Elevated lactate promotes PD‑L1 lactylation and membrane accumulation while suppressing CD8+ T‐cell cytotoxicity, collectively facilitating immune evasion and malignant progression in TNBC.
Yuhan Jin, Wenjing Zhao, Lei Wang, Jianing Wang, Keying Zhao, Dan Luo, Yifei Wang, Yuxia Yang, Jingze Yang, Yaming Li, Tong Chen, Dianwen Han, Zekun Wang, Xiaoyan Li, Bing Chen, Lijuan Wang, Yiran Liang, Qifeng Yang   +17 more
wiley   +1 more source

Beyond CD4: Posterior segment findings and virologic-immunologic predictors in highly active antiretroviral therapy-naïve HIV patients. [PDF]

Indian J Ophthalmol
Hayat SC, Yilmaz YC, Gunduz A, Uran M, Ozal SA.   +4 more
europepmc   +1 more source

Biochemically Constrained Multi‐Omics Integration Reveals Protein–Metabolite Dependencies Across Diseases

Advanced Science, EarlyView.
ProMetNet introduces a biologically constrained deep learning framework for proteo‐metabolomic integration by embedding Reactome‐derived pathway topology into neural networks. It captures non‐linear molecular dependencies and pathway‐level metabolic reorganization, enabling interpretable discrimination.
Minghui Zhao, Na Zhou, Ruotong Liu, Xiaofei Li, Jian Li, Fuzhong Xue, Qingzhen Hou   +6 more
wiley   +1 more source