Results 41 to 50 of about 974,911 (268)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
Daimon, 2021 En este artículo abordaremos la cuestión de los ‘puntos de vista’ desde la propuesta filosófica de Alain Badiou. Para ello, recurriremos especialmente a L’être et l’événement y a los últimos seminarios, destinados a elaborar el material para L’Immanence
Mikel Varela Pequeño
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Pesquisa & psicanálise: algumas referências lacanianas
Psicologia: Teoria e PesquisaEste estudo propõe uma discussão sobre alguns dos parâmetros que orientam a pesquisa no campo da psicanálise, levando-se em conta que esta não se reconhece nos critérios estatísticos e experimentais do discurso da ciência.
Angela Cavalcanti Bernardes
doaj +1 more source
Penentuan Fungsi Linear yang Ideal Pada Model Ekonomi Fungsi Penawaran
Eksis: Jurnal Riset Ekonomi dan Bisnis, 2018 Fenomena ekonomi yang kompleks karena hubungan antar variabel-variabel ekonomi dalam dunia nyata sangatlah kompleks. Fenomena tersebut menjadi sebuah model ekonomi dengan melakukan penyederhanaan.
Tonaas Kabul Wangkok Yohanis Marentek +1 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Estudios Eclesiásticos, 1945 A raíz de la voluminosa obra de investigación que Carlos Giacon, SJ dedicó a Guillermo de Ockam, en el capítulo final de la obra, Giacon recoge en una mirada sintética el rastro dejado por Ockam en la historia de la filosofía y sobre sus influjos en el ...
Jesús Iturrioz
doaj
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source