Results 51 to 60 of about 1,991,944 (311)
Journal of Islamic and Religious Studies, 2022 Islam is a universal religion and an advocate of world-wide peace and unity among people of different backgrounds. It preaches its followers about the unity of the whole humanity. In several verses of Qur’ān and in the sayings of Prophet Muhammad (PBUH),
Syed Muhammad Tahir Shah
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Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
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Llano y la distinción entre universal e individuo
Tópicos, 2013 Llano's proposal yields some problematic implications in ontology and theory of knowledge. Probably, an alternative solution for the problems of accesibility to individuals may depend on a revision of the Aristotelian theory of "faculties".
Héctor Zagal Arreguín
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Daimon, 2021 En este artículo abordaremos la cuestión de los ‘puntos de vista’ desde la propuesta filosófica de Alain Badiou. Para ello, recurriremos especialmente a L’être et l’événement y a los últimos seminarios, destinados a elaborar el material para L’Immanence
Mikel Varela Pequeño
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FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
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Pesquisa & psicanálise: algumas referências lacanianas
Psicologia: Teoria e PesquisaEste estudo propõe uma discussão sobre alguns dos parâmetros que orientam a pesquisa no campo da psicanálise, levando-se em conta que esta não se reconhece nos critérios estatísticos e experimentais do discurso da ciência.
Angela Cavalcanti Bernardes
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Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
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