Results 51 to 60 of about 1,576,879 (317)
Non-Trivial Universes and Sequences of Universes
Formalized Mathematics, 2022 Summary Universe is a concept which is present from the beginning of the creation of the Mizar Mathematical Library (MML) in several forms (Universe, Universe_closure, UNIVERSE) [25], then later as the_universe_of, [33], and recently with the definition GrothendieckUniverse [26], [11], [11].
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Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
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Estudios Eclesiásticos, 1945 A raíz de la voluminosa obra de investigación que Carlos Giacon, SJ dedicó a Guillermo de Ockam, en el capítulo final de la obra, Giacon recoge en una mirada sintética el rastro dejado por Ockam en la historia de la filosofía y sobre sus influjos en el ...
Jesús Iturrioz
doaj
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
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Penentuan Fungsi Linear yang Ideal Pada Model Ekonomi Fungsi Penawaran
Eksis: Jurnal Riset Ekonomi dan Bisnis, 2018 Fenomena ekonomi yang kompleks karena hubungan antar variabel-variabel ekonomi dalam dunia nyata sangatlah kompleks. Fenomena tersebut menjadi sebuah model ekonomi dengan melakukan penyederhanaan.
Tonaas Kabul Wangkok Yohanis Marentek +1 more
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
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Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
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Forma individual o forma individuada
Daimon, 2020 Este artículo pretende ser un diálogo con la posición defendida por Gabriele Galluzzo, dentro de la discusión general acerca de si las formas en el libro Z de la Metafísica son particulares o universales.
Ángel Martínez Sánchez
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
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