Results 221 to 230 of about 816 (272)

Development of a Synthetic Hydrogel to Foster Microvascularization of an Endometriosis Microphysiological System

Advanced Healthcare Materials, EarlyView.
ABSTRACT The ascent of novel alternative methods in drug development spotlights the dual needs for improved biological fidelity to in vivo, along with reproducibility, especially in regulatory applications. The need for pre‐clinical models of patient‐derived endometriosis lesions motivates the development of a vascularizable, completely synthetic ...
Lauren Pruett, Laura Bahlmann, Ryan Ogi, Angela Jiao, Priyatanu Roy, Matthew Johnson, David Trumper, Linda Griffith   +7 more
wiley   +1 more source

Atomate2: modular workflows for materials science.

Digit Discov
Ganose AM, Sahasrabuddhe H, Asta M, Beck K, Biswas T, Bonkowski A, Bustamante J, Chen X, Chiang Y, Chrzan DC, Clary J, Cohen OA, Ertural C, Gallant MC, George J, Gerits S, Goodall REA, Guha RD, Hautier G, Horton M, Inizan TJ, Kaplan AD, Kingsbury RS, Kuner MC, Li B, Linn X, McDermott MJ, Mohanakrishnan RS, Naik AN, Neaton JB, Parmar SM, Persson KA, Petretto G, Purcell TAR, Ricci F, Rich B, Riebesell J, Rignanese GM, Rosen AS, Scheffler M, Schmidt J, Shen JX, Sobolev A, Sundararaman R, Tezak C, Trinquet V, Varley JB, Vigil-Fowler D, Wang D, Waroquiers D, Wen M, Yang H, Zheng H, Zheng J, Zhu Z, Jain A.   +55 more
europepmc   +1 more source

One‐Step Microfluidic Manufactured Fucose‐Decorated Sweetosomes Choose the Time and the Road for Their Intracellular Journey to Cancer Treatment

Advanced Healthcare Materials, EarlyView.
Sweetosomes, a new class of fucose‐decorated liposomes, are developed via a one‐step microfluidic process without surface chemistry. This study elucidates their main caveolae‐mediated entry and distinct endosomal trafficking. These nanostructures demonstrate superior endosomal escape, organelle acidity modulation, and prolonged plasma persistence ...
Mattia Tiboni, Mariele Montanari, Shiva Khorshid, Michele Verboni, Andrea Duranti, Simone Lucarini, Daniele Lopez, Annalisa Aluigi, Gianluca Morganti, Michele Menotta, Giovanna Panza, Daniel J. Klionsky, Barbara Canonico, Luca Casettari   +13 more
wiley   +1 more source

Anonymization: The imperfect science of using data while preserving privacy. [PDF]

Sci Adv
Gadotti A, Rocher L, Houssiau F, Creţu AM, de Montjoye YA.   +4 more
europepmc   +1 more source

Packed for Ossification: High‐Density Bioprinting of hPDC Spheroids in HAMA Toward Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human periosteum‐derived cell spheroids bioprinted at high density within a hyaluronic acid matrix promote fusion and hypertrophic cartilage formation in vitro. Early encapsulation enhances spheroid interaction and matrix maturation, generating scalable cartilage templates intended for endochondral bone regeneration.
Ane Albillos Sanchez, Maria Paula Marks, Paula Casademunt, Adrián Seijas‐Gamardo, Ioannis Papantoniou, Lorenzo Moroni, Carlos Mota   +6 more
wiley   +1 more source

Effect of Proteins on the Network Formation and Degradation of Peroxide Cross-Linked Natural Rubber Elucidated by Time-Domain NMR. [PDF]

Polymers (Basel)
Nimpaiboon A, González-Jiménez A, Pérez-Aparicio R, Martín-Salamanca F, Zepeda-Rodríguez Z, López-Valentín J, Sakdapipanich J.   +6 more
europepmc   +1 more source

Physicochemical Reinforcement Unlocks Sterilization‐Stable Anisotropic Hydrogels for Cell‐Compatible Mock Arteries

Advanced Healthcare Materials, EarlyView.
ABSTRACT In vitro arterial models offer ethical and robust alternatives for vascular research but require cytocompatible materials that replicate physiological mechanics. Poly(vinyl alcohol) (PVA) hydrogels produced by directional freezing and salting‐out (PVA DFSO) are anisotropic yet lack stability for cell culture. Herein, methacrylated PVA (PVA‐MA)
Javiera Sanhueza Ortega, Kirthen Shanmuganathan, Laura Poole‐Warren, Susann Beier, Ulises Aregueta Robles   +4 more
wiley   +1 more source

Artificial intelligence tool development: what clinicians need to know? [PDF]

BMC Med
Chew BH, Ngiam KY.
europepmc   +1 more source

A Data Driven Review of In Vitro Electrical and Mechanical Stimulation for Post‐Acute Phase Wound Healing

Advanced Healthcare Materials, EarlyView.
This review examines how in vitro electrical and mechanical stimulation modulates wound healing in fibroblasts and keratinocytes. Analyzing over 560 experimental data points, we relate stimulation parameters to proliferation and migration outcomes, evaluate platform designs, and highlight the need for multi‐parameter optimization to advance targeted ...
Matthew K. Burgess, Ellen F. Marsh, Veronica M. Lucian, Malavika Nair   +3 more
wiley   +1 more source

3D‐Printed Piezoionic/Bioelectronic Hydrogel for Electro‐Metabolic Regulation of Osteogenic Differentiation

Advanced Healthcare Materials, EarlyView.
A 3D‐printed piezoionic GPMx hydrogel enables stable electromechanical signal generation under mechanical loading, exhibiting long‐term durability and low fatigue. As a bioactive patch, it restores endogenous bioelectricity to stimulate osteogenesis via Ca2+ influx and mitochondrial activation, while simultaneously enabling label‐free alkaline ...
Sayan Deb Dutta, Myoung Joon Jeon, Youjin Seol, Ki‐Taek Lim   +3 more
wiley   +1 more source