Results 91 to 100 of about 1,744,678 (288)
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Universal factorizations of quasiperiodic functions [PDF]
Chirped sinosoids and interferometric phase plots are functions that are not periodic, but are the composition of a smooth function and a periodic function. These functions functions factor into a pair of maps: from their domain to a circle, and from a circle to their codomain.
openaire +2 more sources
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source
Universality Theorems for Some Composite Functions
In [5], it was proved that a collection consisting from Dirichlet L-functions and periodic Hurwitz zeta-functions is universal in the sense that the shifts of those functions approximate simultaneously a given collection of analytic functions.
Kęstutis Janulis +3 more
doaj +1 more source
Hopf algebras and characters of classical groups
Schur functions provide an integral basis of the ring of symmetric functions. It is shown that this ring has a natural Hopf algebra structure by identifying the appropriate product, coproduct, unit, counit and antipode, and their properties.
B Fauser +11 more
core +1 more source
Shared Genetic Effects and Antagonistic Pleiotropy Between Multiple Sclerosis and Common Cancers
ABSTRACT Objective Epidemiologic studies have reported inconsistent altered cancer risk in individuals with multiple sclerosis (MS). Factors such as immune dysregulation, comorbidities, and disease‐modifying therapies may contribute to this variability.
Asli Buyukkurt +5 more
wiley +1 more source
Universal functions of the σ finger in alternative σ factors during transcription initiation by bacterial RNA polymerase. [PDF]
Oguienko A +4 more
europepmc +1 more source
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang +10 more
wiley +1 more source
A universal equation-of-state model based on single variable functions
Since the ideal gas equation of state (EOS) was established in 1840, a wide variety of EOS theories have been developed. However, due to the diversity of material structures and the complexity of intermolecular interactions, numerous EOS either have ...
Ti-Wei Xue, Zeng-Yuan Guo
doaj +1 more source
Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi +19 more
wiley +1 more source

