Results 71 to 80 of about 1,744,678 (288)

Universal relation between Green's functions in random matrix theory

open access: yes, 1995
We prove that in random matrix theory there exists a universal relation between the one-point Green's function $G$ and the connected two- point Green's function $G_c$ given by \vfill $ N^2 G_c(z,w) = {\part^2 \over \part z \part w} \log (({G(z)- G(w ...
't Hooft   +20 more
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Combining activities of the сhief editor and the host of information program: new regional specifics (on the example of GTRK “Vladivostok”)

open access: yesRUDN Journal of Studies in Literature and Journalism, 2019
Universality finds new incarnations in practical journalistic activity. In regional editions a different type of universality appears, expressed in the combination of the activities of the chief editor and the news anchor.
Olga N. Semakina
doaj   +1 more source

Universal and non-universal tails of distribution functions in the directed polymer and KPZ problems

open access: yes, 2008
The optimal fluctuation approach is applied to study the most distant (non-universal) tails of the free-energy distribution function P(F) for an elastic string (of a large but finite length L) interacting with a quenched random potential.
B. I. Shklovskii   +11 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

The Universal Soldier: Enzymatic and Non-Enzymatic Antioxidant Functions of Serum Albumin

open access: yesAntioxidants, 2020
As a carrier of many biologically active compounds, blood is exposed to oxidants to a greater extent than the intracellular environment. Serum albumin plays a key role in antioxidant defence under both normal and oxidative stress conditions.
Daria A. Belinskaia   +6 more
doaj   +1 more source

Superfluid/Bose-glass transition in one dimension

open access: yes, 2014
We consider a one-dimensional system of interacting bosons in a random potential. At zero temperature, it can be either in the superfluid or in the insulating phase. We study the transition at weak disorder and moderate interaction.
Doussal, Pierre Le   +3 more
core   +4 more sources

Universality of Squashed-Sphere Partition Functions [PDF]

open access: yesPhysical Review Letters, 2019
11 pages, 2 figures; v3: minor modifications to match published ...
Bueno, Pablo   +3 more
openaire   +3 more sources

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Universal approximation of continuous functions with minimal quantum circuits

open access: yesPhysical Review Research
The conventional paradigm of quantum computing is discrete: It utilizes discrete sets of gates to realize bitstring-to-bitstring mappings, some of them arguably intractable for classical computers.
Adrián Pérez-Salinas   +3 more
doaj   +1 more source

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