Results 51 to 60 of about 13,786,233 (255)

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Greater political commitment needed to eliminate malaria

Infectious Diseases of Poverty, 2019
Malaria-related mortality has a very high association with poverty rates, and the disease is most prevalent in low- and middle-income countries. To achieve the malaria-specific targets of the Sustainable Development Goals, malaria-endemic countries and ...
Minghui Ren
doaj   +1 more source

The cost of health workforce gaps and inequitable distribution in the Ghana Health Service: an analysis towards evidence-based health workforce planning and management

Human Resources for Health, 2021
Background Despite tremendous health workforce efforts which have resulted in increases in the density of physicians, nurses and midwives from 1.07 per 1000 population in 2005 to 2.65 per 1000 population in 2017, Ghana continues to face shortages of ...
James Avoka Asamani, Hamza Ismaila, Anna Plange, Victor Francis Ekey, Abdul-Majeed Ahmed, Margaret Chebere, John Koku Awoonor-Williams, Juliet Nabyonga-Orem   +7 more
doaj   +1 more source

Achieving universal health coverage

Bulletin of the World Health Organization, 2015
There is global consensus on the goals of universal health coverage (UHC), which has been defined as “all people receiving quality health services that meet their needs without exposing them to financial hardship in paying for them.”1 Yet despite this consensus, it remains unclear how the global health community can achieve universal coverage.
openaire   +3 more sources

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Universal Health Coverage: Why health insurance schemes are leaving the poor behind [PDF]

, 2013
Universal Health Coverage is about the right to health. Everyone - rich or poor - should get the health care they need without suffering financial hardship.
Marriott, Anna, Averill, Ceri
core  

Capacity and service readiness of facilities for non-communicable diseases in Bangladesh: a health system perspective from two selected districts

BMC Health Services Research
Background Non-communicable diseases (NCDs) are a growing health crisis in Bangladesh and a leading cause of morbidity and mortality. This study assessed the capacity and service readiness of healthcare facilities for the management of NCDs, including ...
Masudur Rahman Kanchon, Md. Rakib Akon, Zarin Tasnim, Nahitun Naher, Lamisa Rahman, Nicole Fraser-Hurt, Syed Masud Ahmed   +6 more
doaj   +1 more source

Evaluation of the implementation of hospital hygiene components in 30 health-care facilities in the autonomous district of Abidjan (Cote d’Ivoire) with the WHO Infection Prevention and Control Assessment Framework (IPCAF)

BMC Health Services Research, 2023
Introduction As part of the implementation of its mission “to integrate hygiene activities into healthcare”, the general directorate of health conducted in 2018 with its technical structures, an evaluation of the implementation of Infection Prevention ...
Doumbia Mariamou Cissé, Essis Esme Marie Laure, Koné Atioumounan Blaise, N’gbesso N’gbesso Jean Paul, Mbengue Valérie Gbonon, Cissé Raïssa Adja Mayaka, Gagne Doh Eugénie, Dagnan N’cho Simplice, Kouadio Luc Philippe, Samba Mamadou   +9 more
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source