Results 51 to 60 of about 1,612,376 (366)

Has VZV epidemiology changed in Italy? Results of a seroprevalence study [PDF]

, 2017
The aim of the study was to evaluate if and how varicella prevalence has changed in Italy. In particular a seroprevalence study was performed, comparing it to similar surveys conducted in pre-immunization era.
Amodio E., Angelillo I., Bagordo F., Baldo V., Baldovin T., Bandettini R., Bassetti D., Bassi C., Bella A., Bernardini S., Binda S., Bonanni P., Bordonaro P., Brignole G., Cacello E., Caligiuri P., Casalino P., Castiglia P., Cia M., Cicerchia E., Clerico L., Cracchiolo M., D'Agaro P., De Donno A., Del Manso M., Devoti G., Di Giuseppe G., Ditommaso S., Fazii P., Gabutti G., Gallo T., Gamper A., Giandomenico A. M., Giraldi C., Grasso G., Greco F., Guerra G., Guido M., Idolo A., Kuhdari P., Lupi S., Maglione F., Manchia P., Megha M., Pagani E., Passamonti B., Pellegrinelli L., Pelliccioni A. R., Perrone M., Peruzzi M., Piana A., Primache V., Renzoni C., Resciniti C., Romano P., Rossi P., Rota M. C., Sammarco M. L., Schettini S., Schippa S., Sciuto V., Segat L., Stefanati A., Sticchi L., Tiscione E., Trucchi C., Tumolo M. R., Vallerini M., Vargiu P., Vitale F., Zizza A., Zotti C.   +71 more
core   +1 more source

A single-shot vaccine approach for the universal influenza A vaccine candidate M2e

Proceedings of the National Academy of Sciences of the United States of America, 2022
Significance Although the need for a universal influenza vaccine has long been recognized, only a handful of candidates have been identified so far, with even fewer advancing in the clinical pipeline.
Ranmali Kavishna, Tha Yang Kang, Maurizio Vacca, B. Chua, Hae-Young Park, P. Tan, V. Chow, M. Lahoud, S. Alonso   +8 more
semanticscholar   +1 more source

Hepatitis B Virus (HBV) and S-Escape Mutants: From the Beginning until Now [PDF]

, 2015
Despite of the progress made in vaccine and antiviral therapy development, hepatitis B virus (HBV) infection remains a major health care problem. More than 240 million people are chronically infected worldwide showing differences in the severity of liver
Cuestas, María Luján, Eguibar, Nair, Gonzalez, Rodrigo Horacio, Nusblat, Alejandro David, Perazzo, Priscila   +4 more
core   +1 more source

Safety and immunogenicity of a seasonal trivalent inactivated split influenza vaccine: a phase I randomized clinical trial in healthy Serbian adults

Human Vaccines & Immunotherapeutics, 2018
This study was a phase I double-blind, randomized, placebo-controlled trial to evaluate the safety and immunogenicity of a Serbian-produced seasonal trivalent split, inactivated influenza vaccine in healthy adults. The vaccine was manufactured in eggs by
Goran Stevanovic, Lidija Lavadinovic, Svetlana Filipovic Vignjevic, Renée Holt, Katarina Ilic, Francesco Berlanda Scorza, Erin Sparrow, Vera Stoiljkovic, Guido Torelli, Tamra Madenwald, Muriel Socquet, Aleksandra Barac, Yordanka Ilieva-Borisova, Mijomir Pelemis, Jorge Flores   +14 more
doaj   +1 more source

Bioinformatics Designing and Molecular Modelling of a Universal mRNA Vaccine for SARS-CoV-2 Infection

Vaccines, 2022
At this present stage of COVID-19 re-emergence, designing an effective candidate vaccine for different variants of SARS-CoV-2 is a study worthy of consideration.
E. K. Oladipo, Micheal Oluwafemi Adeniyi, Mercy Temiloluwa Ogunlowo, B. A. Irewolede, Victoria Oluwapelumi Adekanola, Glory Samuel Oluseyi, Janet Abisola Omilola, Anietie Femi Udoh, S. E. Olufemi, D. A. Adediran, Aanuoluwapo Olonade, Usman Abiodun Idowu, O. Kolawole, J. Oloke, H. Onyeaka   +14 more
semanticscholar   +1 more source

Antibody Focusing to Conserved Sites of Vulnerability: The Immunological Pathways for ‘Universal’ Influenza Vaccines

Vaccines, 2021
Influenza virus remains a serious public health burden due to ongoing viral evolution. Vaccination remains the best measure of prophylaxis, yet current seasonal vaccines elicit strain-specific neutralizing responses that favor the hypervariable epitopes ...
Maya Sangesland, Daniel Lingwood
doaj   +1 more source

Universal Flu mRNA Vaccine: Promises, Prospects, and Problems

Vaccines, 2022
The seasonal flu vaccine is, essentially, the only known way to prevent influenza epidemics. However, this approach has limited efficacy due to the high diversity of influenza viruses. Several techniques could potentially overcome this obstacle. A recent
A. Deviatkin, Ruslan A Simonov, K. Trutneva, A. Maznina, E. Khavina, P. Volchkov   +5 more
semanticscholar   +1 more source

Long-lasting cross-protection against influenza A by neuraminidase and M2e-based immunization strategies [PDF]

, 2016
There is mounting evidence that in the absence of neutralizing antibodies cross-reactive T cells provide protection against pandemic influenza viruses. Here, we compared protection and CD8+ T cell responses following challenge with H1N1 2009 pandemic and
Callewaert, Nico, Fiers, Walter, Saelens, Xavier, Schepens, Bert, Schotsaert, Michael, Smet, Anouk, Stegalkina, Svetlana, Vanderschaeghe, Dieter, Vogel, Thorsten U, Ysenbaert, Tine   +9 more
core   +2 more sources

Universal influenza vaccines: from viruses to nanoparticles

Expert Review of Vaccines, 2018
Introduction: The current seasonal influenza vaccine confers only limited protection due to waning antibodies or the antigenic shift and drift of major influenza surface antigens. A universal influenza vaccine which induces broad cross-protection against
Ye Wang, Lei Deng, Sang-Moo Kang, Bao-Zhong Wang   +3 more
doaj   +1 more source

Options and Obstacles for Designing a Universal Influenza Vaccine

Viruses, 2014
Since the discovery of antibodies specific to a highly conserved stalk region of the influenza virus hemagglutinin (HA), eliciting such antibodies has been considered the key to developing a universal influenza vaccine that confers broad-spectrum ...
Yo Han Jang, Baik Lin Seong
doaj   +1 more source