Results 31 to 40 of about 524,435 (262)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

DAKWAH DALAM MASYARAKAT MULTIKULTURAL

open access: yesKomunika, 2015
Indonesia is a country which has so many ethnicities, tribes, cultures, languages, and religions. Such diversity is prone to conflict and discord and therefore, there must be a systematic, programmed, integrated, and sustainable effort to maintain the ...
Nawawi Nawawi
doaj   +3 more sources

Fiqh Sosial Paradigm for Understanding Universal Values of Pancasila

open access: yesSantri, 2023
This paper is the result of research on interpreting universal values ​​of Pancasila according to the paradigm of fiqh sosial. This research is a qualitative research. This research uses a descriptive method.
Tutik Nurul Janah, Siti Nur Ami'in
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

How Transformative Experiences Reshape Values, Worldviews, and Engagement with Sustainability: An Integral Inquiry

open access: yesChallenges
Climate scientists, systems theorists, and policymakers increasingly suggest that global sustainability challenges stem from dysfunctional worldviews and values that drive individual and collective behaviors, undermining both human flourishing and ...
Elizabeth Halliday, Jessica Bockler
doaj   +1 more source

Review of international media ethics

open access: yesComunicação e Sociedade, 2014
An international orientation has been a primary goal of media ethics, especially since the MacBride Report (1980), as can be seen in cases, issues and codes of ethics that have been adopted in different countries. But work in ethical theory has also been
Clifford G. Christians
doaj   +1 more source

Universal Values of Pancasila in Managing the Crime of Terrorism

open access: yesCosmopolitan Civil Societies: An Interdisciplinary Journal, 2023
Using a Socio-Legal Studies approach, this article analyses the primacy of the universal values of Pancasila, a decolonizing ideology, in tackling crimes of terrorism in Indonesia.
Joko Setiyono, Aga Natalis
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

A Critical Dialogue on the Cosmopolitan Turn in Communication Studies

open access: yesGlobal Media Journal: German Edition
This discussion engages with the collective volume Cosmopolitan Communication Studies: Toward Deep Internationalization. The editors and contributors call for a cosmopolitan reorientation of communication studies that transcends enduring Eurocentric ...
Anke Fiedler   +5 more
doaj   +1 more source

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