Results 61 to 70 of about 19,595 (293)

ECUACIONES PARA CONTROLADORES PID UNIVERSALES

open access: yesIngeniería, 2011
Se propone la utilización de solamente dos ecuaciones para representar a los controladores PID. El controlador PID Universal tipo Paralelo (PIDup) y el controlador PID Universal tipo Serie (PIDus), junto con un conjunto único de parámetros que permiten ...
Víctor M. Alfaro Ruíz
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Nueve tesis sobre los universales según Policraticus y Metalogicon de Juan de Salisbury

open access: yesPatristica et Mediaevalia, 2011
En este trabajo presentamos las críticas a los maestros de la dialéctica y sus nueve opiniones sobre la naturaleza de los universales de Juan de Salisbury expuestas en Policraticus, VII, 12 y Metalogicon, II, 17-19.
Antonio Tursi
doaj  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Modelo de ecuaciones estructurales con variables influyentes en la calidad de vida urbana. Caso de estudio: ciudad de Cienfuegos, Cuba

open access: yesIngeniare: Revista Chilena de Ingeniería
Este artículo presenta un modelo de ecuaciones estructurales que mide la calidad de vida urbana (CVU), tomando como referencia la ciudad de Cienfuegos (Cuba).
Daylí Covas Varela   +3 more
doaj  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Crisis de las comunidades, crisis de los universales

open access: yesRevista Chuy, 2019
Intervención de apertura de la Jornada "Totalidades quebradas. Lecturas de pasado y presente" organizadas por el PELCC en el Ateneu Candela (Terrassa, Barcelona: jueves 29 de septiembre de 2016), en el marco del proyecto internacional “Narrativas ...
Daniel Link
doaj  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

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