Results 31 to 40 of about 288,346 (317)
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Sukob Titovog koncepta univerzalizma i Sukarnovog koncepta regionalizma na samitu nesvrstanih u Kairu 1964. [PDF]
Istorija 20. Veka, 2017 During the Conference of the leaders of non-aligned countries in Cairo, a problem related to the future cooperation and organized international performance of non-aligned countries occurred, without whose resolution it was not possible to go further.
Dragan Bogetić
doaj +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Social security, redistribution and public opinion [PDF]
, 1999 This CASEbrief summarises 'Social security, selective universalism and patchwork redistribution' by John Hills and Orsolya Lelkes in British Social Attitudes, the 16th Report: Who shares New Labour values? edited by R. Jowell, J. Curtice, A.
Hills, John, Lelkes, Orsolya
core
Rawls’s Justification Model for Ethics: What Exactly Justifies the Model? [PDF]
, 2020 This is a defense of Rawls against recent criticism, ironically my own, though it is also a critique insofar as it addresses a problem that Rawls never does. As a defense, it is not a retraction of the original charges.
Alican, Necip Fikri
core
New Challenges for Nordic Welfare Services: 'Emerging Cultural Diversity in Finnish Youth Work'
Nordic Journal of Migration Research, 2014 This article summarises the results of a two-phase research project, which concentrated on leisure practices of ethnic minority youth and their expectations on multicultural youth services.
Pirkkoliisa Ahponen +7 more
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Universalism and Utilitarianism: An Evaluation of Two Popular Moral Theories in Business Decision Making [PDF]
, 2015 Moral theories remain a topic of interest, not just to moral philosophers, but increasingly in business circles as well, thanks to a tainted reputation that urges more awareness in this regard.
Marques, Joan
core +2 more sources
Values Following a Major Terrorist Incident: Finnish Adolescent and Student Values Before and After September 11, 2001 [PDF]
, 2006 The horrific terrorist attacks on the United States on September 11, 2001, left an indelible mark on perceptions of security and threat across the world.
Applewhite +35 more
core +2 more sources
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source