Results 51 to 60 of about 15,075 (306)

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Public service media in the era of information disorder : Collaboration as a solution for achieving universalism

, 2020
Viral false information, siloed information habits, and growing distrust in the media are amongst today’s most alarming challenges to digital media markets.
Aslama Horowitz, Minna, Lowe, Gregory Ferrell   +1 more
core   +1 more source

Contextualism Revisited: Towards a More Relevant Conceptualization of Public Administration for Ethical and Sustainable Leadership in the Global Context [PDF]

Theoretical and Applied Economics, 2008
The paper examines how the contextual approach to the conceptualization and the design of public administration systems can still be a viable alternative for today’s environment.
Asghar Zomorrodian
doaj  

Unsettling the regime of human rights: Decolonial reflections beyond the law

Sortuz, 2022
In this article we strive to problematize and unsettle the regime of human rights, critically reflecting around their potential for decolonization. Although the discourse of human rights has been used by multiple actors for the last decades as a tool to ...
Juan Martín Liotta, Amadeo Szpiga
doaj  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

University Administration and University Ideals [PDF]

Science, 1911
n ...
openaire   +2 more sources

Non-Trivial Universes and Sequences of Universes

Formalized Mathematics, 2022
Summary Universe is a concept which is present from the beginning of the creation of the Mizar Mathematical Library (MML) in several forms (Universe, Universe_closure, UNIVERSE) [25], then later as the_universe_of, [33], and recently with the definition GrothendieckUniverse [26], [11], [11].
openaire   +2 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

“How much satisfaction can I get from a court order for somebody to associate with me who does not wish me near them?” Accounting for Zora Neale Hurston’s Opposition to Desegragation as a Defiance of Universalism

Miranda: Revue Pluridisciplinaire du Monde Anglophone
The political considerations that presided over both the fall into oblivion and the rehabilitation of Zora Neale Hurston’s literary and anthropological work are in fact different readings of her stance towards universalism.
Carline Encarnación
doaj   +1 more source

Reclaiming Romani-ness

Critical Romani Studies, 2018
Drawing on theories of identity postulated by cultural theorists, scholars of gender identity, and critical race theorists, I explore issues of identity politics and “Otherness” as they pertain to Romani identity, history and activism.
Ioanida Costache
doaj   +1 more source