Results 51 to 60 of about 21,449 (288)
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Rivista di EsteticaKant is famous for his doctrine of moral universalism. But in his writings on anthropology, physical geography, and history, he distinguished between four different human races, claiming that only members of the white, European race had developed the ...
Christel Fricke
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Universalism and Queer Entanglements
Miranda: Revue Pluridisciplinaire du Monde AnglophoneGiven the rapid homogenisation of queer discourse transnationally through its attachment to Euro-US avatars, it has become commonplace to consider the normativity of the queer-as-antinormative narrative as a “field-defining rule” (Wiegman and Wilson ...
Sandeep Bakshi
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HAMLET AND GJORG BERISHA: A COMPARATIVE STUDY OF CHARACTERS [PDF]
Езиков святThe art of literature has brought together the experiences of human society and foregrounded various artistic values. The effort to examine the elements of universalization in literature through the perspective of juxtaposition is an innovation of this
Butrint Balaj, Vjollca Dibra
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Religions, 2020 The rush of Western civilization, headed by Christianity, caused a considerable identity crisis in the 19th century Joseon dynasty. The founder of Donghak 東學, Suun Choe Je-u 水雲 崔濟愚, sought a way out of the crisis through religion. Suun contended that the
Haeyoung Seong
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Non-Trivial Universes and Sequences of Universes
Formalized Mathematics, 2022 Summary Universe is a concept which is present from the beginning of the creation of the Mizar Mathematical Library (MML) in several forms (Universe, Universe_closure, UNIVERSE) [25], then later as the_universe_of, [33], and recently with the definition GrothendieckUniverse [26], [11], [11].
openaire +2 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source