Results 71 to 80 of about 21,449 (288)
La traite et l’esclavage colonial français dans notre mémoire nationale
SocioThis article explores the need for memory work.
Jean-Marc Ayrault
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Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Déplacements, décentrages : le roman en transit
Brésil(s), 2015 This article proposes the notions of displacement and decentering, in order to explore the possibilities presented by understanding the novel as a transnational genre, that is, a genre which, despite being rooted in specific contexts, has traversed or ...
Sandra Guardini Teixeira Vasconcelos
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Making Universal Policies Universal
International Joint Conference on Autonomous Agents and Multiagent SystemsThe development of a generalist agent capable of solving a wide range of sequential decision-making tasks remains a significant challenge. We address this problem in a cross-agent setup where agents share the same observation space but differ in their action spaces.
Hoepner, Niklas +2 more
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Learning at the University - conceptions of university teachers
, 2020 Academia, No 22 (2021)
Chaleta, Elisa, Saraiva, Margarida
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The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
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Marx\u27s Political Universalism [PDF]
, 1996 My main aim in this paper is to arrive at a defensible form of Marxian or socialist political universalism through a critical examination of Marx\u27s own political universalism.
van der Linden, Harry
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The Idea of the Integrity of Social Being in Russian Religious Philosophy
Управленческое консультированиеThe article considers the understanding of the nature of public life as some integrity in Russian religious philosophy. It is shown that the main specificity of the way of thinking of Russian philosophers is to distinguish between the empirical reality ...
V. B. Aleksandrov
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