Results 61 to 70 of about 1,002,978 (334)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
The effects of welfare state universalism on migrant integration
Policy and politics (Print), 2019 This paper investigates how and why welfare state universalism can shape the integration of migrants into the national community. Universalism is broadly regarded as central to the integrative and solidarity-building potential of welfare states, but we ...
Anthony Kevins, K. van Kersbergen
semanticscholar +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Rivista di EsteticaKant is famous for his doctrine of moral universalism. But in his writings on anthropology, physical geography, and history, he distinguished between four different human races, claiming that only members of the white, European race had developed the ...
Christel Fricke
doaj +1 more source
Rethinking of the Crisis of Universalism: Toward a Pluralistic Orientation of Cosmopolitanism
Interlitteraria, 2019 In commemorating the centenary of the end of World War I, we could not but reflect on many of the valuable legacies and lessons the War has left behind it.
Ning Wang
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Universalism and Queer Entanglements
Miranda: Revue Pluridisciplinaire du Monde AnglophoneGiven the rapid homogenisation of queer discourse transnationally through its attachment to Euro-US avatars, it has become commonplace to consider the normativity of the queer-as-antinormative narrative as a “field-defining rule” (Wiegman and Wilson ...
Sandeep Bakshi
doaj +1 more source