Results 61 to 70 of about 21,449 (288)

Contextualism Revisited: Towards a More Relevant Conceptualization of Public Administration for Ethical and Sustainable Leadership in the Global Context [PDF]

open access: yesTheoretical and Applied Economics, 2008
The paper examines how the contextual approach to the conceptualization and the design of public administration systems can still be a viable alternative for today’s environment.
Asghar Zomorrodian
doaj  

Unsettling the regime of human rights: Decolonial reflections beyond the law

open access: yesSortuz, 2022
In this article we strive to problematize and unsettle the regime of human rights, critically reflecting around their potential for decolonization. Although the discourse of human rights has been used by multiple actors for the last decades as a tool to ...
Juan Martín Liotta, Amadeo Szpiga
doaj  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Universalism(e) & …

open access: yes
Those who look for the traces of a new universalism of our time are themselves its critical builders. The conversations documented in this book echo recordings of encounters online, and sow their own traces of a minor universalism that can be imagined in-

core   +1 more source

“How much satisfaction can I get from a court order for somebody to associate with me who does not wish me near them?” Accounting for Zora Neale Hurston’s Opposition to Desegragation as a Defiance of Universalism

open access: yesMiranda: Revue Pluridisciplinaire du Monde Anglophone
The political considerations that presided over both the fall into oblivion and the rehabilitation of Zora Neale Hurston’s literary and anthropological work are in fact different readings of her stance towards universalism.
Carline Encarnación
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Reclaiming Romani-ness

open access: yesCritical Romani Studies, 2018
Drawing on theories of identity postulated by cultural theorists, scholars of gender identity, and critical race theorists, I explore issues of identity politics and “Otherness” as they pertain to Romani identity, history and activism.
Ioanida Costache
doaj   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

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