Results 111 to 120 of about 419,064 (295)
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Translational Universality: The Struggle over the Universal
The aim of this paper is to investigate the idea of universality through the lens of translation, in an attempt to sketch out what can be called a translational universality.
Saša Hrnjez
doaj
In the category of left modules over a unital ring we show that a left exact reflector determines, for each n⩾1, a torsion theoretic setting in which universal extensions of length n exist. Combined with recent work of Rodelo and van der Linden (2011) [9] this establishes the existence of universal central extensions of groups and Lie algebras ...
openaire +2 more sources
Objective The objective was to identify factors determining acute arthritis resolution and safety with colchicine and prednisone in acute calcium pyrophosphate (CPP) crystal arthritis. Methods We conducted a post hoc analysis of the COLCHICORT trial, which compared colchicine and prednisone for the treatment of acute CPP crystal arthritis, using a ...
Tristan Pascart +14 more
wiley +1 more source
Probability distribution functions in turbulent convection [PDF]
Results of an extensive investigation of probability distribution functions (pdfs) for Rayleigh-Benard convection, in hard turbulence regime, are presented. It is shown that the pdfs exhibit a high degree of internal universality.
Balachandar, S., Sirovich, L.
core +1 more source
Objective We evaluated the role of 25‐hydroxyvitamin D (25[OH]D), prednisone, and other risk factors for bone mineral density (BMD) loss and osteoporosis in systemic lupus erythematosus (SLE). Methods We calculated the association between 25(OH)D levels and other potential risk factors and BMD measures (spine T scores) and osteoporosis (defined as a T ...
Nima Madanchi +4 more
wiley +1 more source
Education and the Attribution of Emotion to Facial Expressions
Certain facial expressions have been proposed to be signals evolved to communicate a single specific emotion. Evidence to support this view is based primarily on university-educated Western adults. In the current study (N=96), university-educated and non-
Nicole M Trauffer +2 more
doaj
Lepton Flavour Universality tests in $B$ decays as a probe for New Physics
In the Standard Model (SM), the coupling of the electroweak gauge bosons to the leptons is lepton flavour universal. Tests of this property constitute sensitive probes for new physics models that violate lepton flavour universality.
Langenbruch, Christoph
core
Objective We investigated whether a diagnosis of rheumatoid arthritis (RA) affects the quality of inpatient acute myocardial infarction (AMI) care and long‐term mortality post‐AMI. Methods We analyzed data from 784,091 adults, 6,047 with a diagnosis of RA, from England and Wales hospitalized with AMI between 2005 and 2019 from the Myocardial Ischaemia ...
Megan Butler +8 more
wiley +1 more source
Universality of human rights and cultural diversity: A Perspective [PDF]
Colloquium presentation - no abstract ...
L Wessels
doaj

