Results 111 to 120 of about 419,064 (295)

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan   +9 more
wiley   +1 more source

Translational Universality: The Struggle over the Universal

open access: yesLabyrinth: An International Journal for Philosophy, Value Theory and Sociocultural Hermeneutics, 2020
The aim of this paper is to investigate the idea of universality through the lens of translation, in an attempt to sketch out what can be called a translational universality.
Saša Hrnjez
doaj  

Universal extensions

open access: yesComptes Rendus. Mathématique, 2011
In the category of left modules over a unital ring we show that a left exact reflector determines, for each n⩾1, a torsion theoretic setting in which universal extensions of length n exist. Combined with recent work of Rodelo and van der Linden (2011) [9] this establishes the existence of universal central extensions of groups and Lie algebras ...
openaire   +2 more sources

Exploring Patients’ Profiles Associated With the Resolution of Acute Calcium Pyrophosphate Arthritis Treated With Colchicine and Prednisone: Post Hoc Analysis of a Randomized Controlled Trial

open access: yesArthritis Care &Research, EarlyView.
Objective The objective was to identify factors determining acute arthritis resolution and safety with colchicine and prednisone in acute calcium pyrophosphate (CPP) crystal arthritis. Methods We conducted a post hoc analysis of the COLCHICORT trial, which compared colchicine and prednisone for the treatment of acute CPP crystal arthritis, using a ...
Tristan Pascart   +14 more
wiley   +1 more source

Probability distribution functions in turbulent convection [PDF]

open access: yes
Results of an extensive investigation of probability distribution functions (pdfs) for Rayleigh-Benard convection, in hard turbulence regime, are presented. It is shown that the pdfs exhibit a high degree of internal universality.
Balachandar, S., Sirovich, L.
core   +1 more source

Role of Prednisone and 25‐Hydroxyvitamin D on Bone Mineral Density and Osteoporosis in Systemic Lupus Erythematosus

open access: yesArthritis Care &Research, EarlyView.
Objective We evaluated the role of 25‐hydroxyvitamin D (25[OH]D), prednisone, and other risk factors for bone mineral density (BMD) loss and osteoporosis in systemic lupus erythematosus (SLE). Methods We calculated the association between 25(OH)D levels and other potential risk factors and BMD measures (spine T scores) and osteoporosis (defined as a T ...
Nima Madanchi   +4 more
wiley   +1 more source

Education and the Attribution of Emotion to Facial Expressions

open access: yesPsychological Topics, 2013
Certain facial expressions have been proposed to be signals evolved to communicate a single specific emotion. Evidence to support this view is based primarily on university-educated Western adults. In the current study (N=96), university-educated and non-
Nicole M Trauffer   +2 more
doaj  

Lepton Flavour Universality tests in $B$ decays as a probe for New Physics

open access: yes, 2018
In the Standard Model (SM), the coupling of the electroweak gauge bosons to the leptons is lepton flavour universal. Tests of this property constitute sensitive probes for new physics models that violate lepton flavour universality.
Langenbruch, Christoph
core  

Temporal Trends and Short‐ and Long‐Term Mortality of People With Acute Myocardial Infarction and Rheumatoid Arthritis: A Nationwide Cohort Study

open access: yesArthritis Care &Research, EarlyView.
Objective We investigated whether a diagnosis of rheumatoid arthritis (RA) affects the quality of inpatient acute myocardial infarction (AMI) care and long‐term mortality post‐AMI. Methods We analyzed data from 784,091 adults, 6,047 with a diagnosis of RA, from England and Wales hospitalized with AMI between 2005 and 2019 from the Myocardial Ischaemia ...
Megan Butler   +8 more
wiley   +1 more source

Universality of human rights and cultural diversity: A Perspective [PDF]

open access: yesPotchefstroom Electronic Law Journal, 2003
Colloquium presentation - no abstract ...
L Wessels
doaj  

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