Results 111 to 120 of about 1,114,161 (348)

Insurgent Universality

open access: yesHistorical Materialism, 2019
Insurgent Universality presents an intervention in current discussions on universalism, democracy, and property. It investigates other trajectories besides traditional ones of modernity and traces an alternative legacy for contemporary movements.
Massimiliano Tomba
semanticscholar   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

open access: yesMolecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi   +2 more
wiley   +1 more source

Making Universal Policies Universal

open access: yesInternational Joint Conference on Autonomous Agents and Multiagent Systems
The development of a generalist agent capable of solving a wide range of sequential decision-making tasks remains a significant challenge. We address this problem in a cross-agent setup where agents share the same observation space but differ in their action spaces.
Hoepner, Niklas   +2 more
openaire   +3 more sources

On the Universality of Hawking Radiation [PDF]

open access: yes, 2018
A physically consistent semi-classical treatment of black holes requires universality arguments to screen late-time Hawking radiation from ultra-short distance near-horizon effects.
Palacios, Patricia   +4 more
core   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Reading Provincializing Europe as a Missed Opportunity

open access: yesPráticas da História, 2020
This essay explores Chakrabarty’s introduction of the expression “provincializing Europe” as a privileged way of understanding history in modern conditions.
Réal Fillion
doaj   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

Connecting Glass-Forming Fragility to Network Topology

open access: yesFrontiers in Materials, 2019
Glass fragility is a byproduct of early attempts to apply law of corresponding states scaling to the temperature dependent thickening of glass forming liquids. Efforts to plot the logarithm of the viscosity vs.
David L. Sidebottom
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

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