Results 81 to 90 of about 1,114,161 (348)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The TPNW Conference of Parties: What Is to Be Discussed?
Journal for Peace and Nuclear Disarmament, 2020 The Treaty on the Prohibition of Nuclear Weapons (TPNW) is one of the most important developments of the modern era. This paper addresses the question posed, of what issues are to be discussed at the 1st Conference of the States Parties to the Treaty ...
Kennedy Graham
doaj +1 more source
Moral category of human rights in the country’s defense [PDF]
Војно дело, 2016 Nowadays the world is defined and essentially functions through the idea of law and justice. Human rights are among basic values of modern civilization and are becoming a matter of general concern and international responsibility.
Narančić Mane
doaj +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Music: Specialized to Integrate?
Empirical Musicology Review, 2015 In her paper Schaefer (2014) provides a relevant amount of behavioral and neuroimaging evidence within and outside the realm of music favoring the notion that predictive processing plays a prominent role in the coupling of perception, cognition and ...
Paulo Estêvão Andrade +1 more
doaj +1 more source
Universality of Büchi automata ::analysis with graph neural networks
, 2023 The universality check of Büchi automata is a foundational problem in automata-based formal verification, closely related to the complementation problem, and is known to be PSPACE-complete.
Ultes-Nitsche, Ulrich +2 more
core +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Universality and diversity in human song
, 2018 What is universal about music across human societies, and what varies? We built a corpus of ethnographic text on musical behavior from a representative sample of the world’s societies and a discography of audio recordings of the music itself.
Samuel A. Mehr +18 more
semanticscholar +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Critical remarks on Religion in the public sphere' – Habermas between Kant and Kierkegaard
Etikk i Praksis: Nordic Journal of Applied Ethics, 2009 This article provides a critical assessment of Habermas's recent work on religion and the role of religion in the public sphere by comparing it to Kant's philosophy of religion on the one hand and that of Kierkegaard on the other.
Roe Fremstedal
doaj +1 more source