Results 111 to 120 of about 113,830 (296)

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

open access: yesMolecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad   +13 more
wiley   +1 more source

Universics: a Theory of Universes of Discourse for Metamathematics and Foundations [PDF]

open access: yesComputer Science Journal of Moldova, 2016
A new type of structures called ``universes'' is introduced to subsume the ``von Neumann universe'', ``Grothendieck universes'' and ``universes of discourse'' of various theories.
Ioachim Drugus
doaj  

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

open access: yesMolecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran   +16 more
wiley   +1 more source

Efforts to Save the Universe: Muhammadiyah's Concern for the Environment

open access: yesSuhuf
Muhammadiyah as a part of the civilization has a responsibility to spread the mercy. The organization that founded by KH Ahmad Dahlan is not carrying the theme "Efforts to Save the Universe" for its 111th anniversary in 2023 without reason.
Shubhi Mahmashony Harimurti   +1 more
doaj   +1 more source

Pythagorean Philolaus’ Pyrocentric Universe [PDF]

open access: yesSCHOLE, 2009
In this work, first, I reexamine the pyrocentric universe of the Pythagorean, Philolaus, who emphatically propounded that the center of the cosmos is neither the earth nor the sun, but a central fiery hearth that stands in the middle of the spherical ...
Maniatis, Yiorgo
doaj  

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

open access: yesMolecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy   +12 more
wiley   +1 more source

PEDAGOGY OF UNIVERSAL ARTISTIC THOUGHT

open access: yesRussian Journal of Education and Psychology
Background. The article examines the phenomenon of artistic and imaginative thinking and its formation in humans as a pedagogical reality. The problem is as important as it is poorly studied in the literature.
Pavel A. Gagaev
doaj   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

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