Results 91 to 100 of about 1,434,875 (336)

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Deflationary Universe Scenario

open access: yes, 1993
We show that it is possible to realize an inflationary scenario even without conversion of the false vacuum energy to radiation. Such cosmological models have a deflationary stage in which $Ha^2$ is decreasing and radiation produced by particle creation ...
Albrecht   +16 more
core   +2 more sources

Universal Peptidomimetics [PDF]

open access: yesJournal of the American Chemical Society, 2010
This paper concerns peptidomimetic scaffolds that can present side chains in conformations resembling those of amino acids in secondary structures without incurring excessive entropic or enthalpic penalties. Compounds of this type are referred to here as minimalist mimics.
Eunhwa, Ko   +5 more
openaire   +2 more sources

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle   +5 more
wiley   +1 more source

Man as Microcosm and the Universe as Macrocosm in Mulla Sadra's Transcendent Philosophy [PDF]

open access: yesحکمت و فلسفه, 2005
The foundation and corner stone ef Mulla Sadra's attitude toiuards man depends on his whole philosophical system of Transcendent PhilosopfD, tuhich is plunged deep!J into his metapysical vieiv efman as a microcosm in whom creation returns to its source ...
reza akbarian
doaj   +1 more source

Curvature tension: Evidence for a closed universe [PDF]

open access: yes, 2019
The curvature parameter tension between Planck 2018, cosmic microwave background lensing, and baryon acoustic oscillation data is measured using the suspiciousness statistic to be 2.5 to 3$\sigma$.
Will Handley
semanticscholar   +1 more source

Pediatric Oncology Nursing Competencies in Latin America and the Caribbean: A Scoping Review to Inform Practice, Education, and Research

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Nurses are central to cancer care for children and adolescents, yet no comprehensive synthesis has defined essential core competencies for pediatric oncology nursing (PON) practice internationally, particularly in Latin America and the Caribbean (LAC).
Luís Carlos Lopes‐Júnior   +7 more
wiley   +1 more source

Does information entropy play a role in the expansion and acceleration of the Universe?

open access: yes, 2017
We propose an interpretation of the expansion and acceleration of the Universe from an information theoretic viewpoint. We obtain the time evolution of the configuration entropy of the mass distribution in a static Universe and show that the process of ...
Pandey, Biswajit
core   +1 more source

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel   +3 more
wiley   +1 more source

The Thermodynamic Universe

open access: yes, 2008
Using Planck scale oscillators in the background dark energy in a model that parallels the theory of phonons, we deduce the Planck mass, the elementary particle mass scale, the mass of the Universe and a recently discovered residual energy in the cosmic ...
Sidharth, Burra G.
core   +2 more sources

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