Results 81 to 90 of about 1,434,875 (336)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Efforts to Save the Universe: Muhammadiyah's Concern for the Environment

open access: yesSuhuf
Muhammadiyah as a part of the civilization has a responsibility to spread the mercy. The organization that founded by KH Ahmad Dahlan is not carrying the theme "Efforts to Save the Universe" for its 111th anniversary in 2023 without reason.
Shubhi Mahmashony Harimurti   +1 more
doaj   +1 more source

The Philosophical Aspects of the Dialogue between Modern Cosmology and Theology

open access: yesДискурс, 2021
Introduction. The paper deals with the philosophical problems of the modern dialogue between cosmology and theology. It is argued that no existential contradiction is possible between them as originating in one and the same human condition.
A. V. Nesteruk, A. V. Soldatov
doaj   +1 more source

Exponential Cardassian Universe

open access: yes, 2005
The expectation of explaining cosmological observations without requiring new energy sources is forsooth worthy of investigation. In this letter, a new kind of Cardassian models, called exponential Cardassian models, for the late-time universe are ...
Amarzguioui   +42 more
core   +1 more source

Discovery of a supernova explosion at half the age of the Universe [PDF]

open access: yesNature, 1997
The ultimate fate of the Universe, infinite expansion or a big crunch, can be determined by using the redshifts and distances of very distant supernovae to monitor changes in the expansion rate.
S. Perlmutter   +22 more
semanticscholar   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait   +23 more
wiley   +1 more source

Man and Universe

open access: yesТеорія і практика правознавства, 2019
The knowledge of the Universe is an integral part of understanding of human nature. People can perceive themselves, their nature, essence, relations with other people only through learning and understanding the world, the laws of evolution and existence.
Valentina Petrovna Simonok
doaj   +1 more source

The Copernican Principle in Compact Spacetimes

open access: yes, 2003
Copernicus realised we were not at the centre of the universe. A universe made finite by topological identifications introduces a new Copernican consideration: while we may not be at the geometric centre of the universe, some galaxy could be.
Barrow   +21 more
core   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson   +3 more
wiley   +1 more source

The Cosmos and Human Beings from an Interdisciplinary Perspective. “Paradigmatické zmeny v chápaní kozmologickej a antropologickej problematiky. Minulosť a súčasnosť,” [“Paradigmatic Changes in the Understanding of Cosmological and Anthropological Issues. Past and Present”] edited by Zlatica Plašienková, Univerzita Komenského v Bratislave, Bratislava 2021, pp. 308 (rev.)

open access: yesStudia Philosophiae Christianae, 2023
This book presents a complex picture of the universe and man from historical and contemporary perspectives, including philosophical, theological, and scientific perspectives. It consists of several papers by authors from various fields, and it is divided
Štefan Zolcer
doaj   +1 more source

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