Results 111 to 120 of about 244,018 (297)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

The large-scale Structure and dynamics of the local universe [PDF]

open access: yes, 2007
This thesis investigates the dynamics of the local Universe with particular reference to discovering the source of the Local Group (LG) motion. A redshift survey of the Great Attractor (GA) region, thought responsible for a significant fraction of the LG
Radburn-Smith, David James
core  

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

AŞKIN (SEVGİNİN) GÜCÜ

open access: yesFelsefe Dünyası, 2005
Ömer ÖZDEN, AŞKIN (SEVGİNİN) GÜCÜ, FELSEFE DÜNYASI DERGİSİ, SAYI:42 ...
Ömer Özden
doaj  

The Problem of Unity and Plurality in Teftâzânî

open access: yesDin ve Bilim Muş Alparslan Üniversitesi İslami İlimler Fakültesi Dergisi
In the religious texts of Muslims, some commands praise all forms of wisdom and emphasize the necessity of acquiring wisdom wherever it is found. For this reason, from the early periods, the Islamic intellectual movement made great efforts to become ...
Ekrem UĞURLU
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

İnsanın Yabancılaşmasına Yönelik Sȗfȋ Perspektif / Sufi Perspective of Human Alienation / اغتراب الإنسان من خلال المنظور الصوفي

open access: yesİlahiyat Akademi, 2016
En büyük kriz insanlık krizidir. Ekonomik, sosyal, siyasal ve kültürel krizler belki bir şekilde aşılabilir ama insanlık krizi tamiri kolay olmayan büyük yaralar açar. O nedenle en büyük yatırım insana yapılan yatırımdır.
Kadir Özköse
doaj  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

“Tüm” (Kull) Kavramı ve Geçmişe Matuf Varlıklar Zincirine Dair Hükme Etkisi: İbn Teymiyye Metinleri Üzerinden Bir Okuma

open access: yesAnkara Üniversitesi İlahiyat Fakültesi Dergisi
Bu çalışmada, İbn Teymiyye’nin (ö. 728/1328) evrene matuf varlıklar zincirine verdiği hükmün, benimsediği “tüm” (kull) kavramıyla ilişkisi ele alınmıştır.
Cihan Özaykan
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

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