Results 121 to 130 of about 119,582 (299)
The Order and Chaos in Human Relationships: Objective Grounds and the Ways of Harmonization
Antropologìčnì Vimìri Fìlosofsʹkih Doslìdžen'Purpose. This article aims to provide a philosophical analysis of disharmonious relations between people in society, to reveal the causes of existing conflicts and to find ways to reduce the manifestations of chaos in human relations.
V. M. Shapoval, I. V. Tolstov
doaj +1 more source
Acceleration of the Universe, String Theory and a Varying Speed of Light [PDF]
, 2001 J. W. Moffat
openalex +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Hierarchy of Fundamental Interactions in Wave Universe [PDF]
, 2001 A. M. Chechelnitsky
openalex +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Actual Picture of the Law of Universal Gravitation and the Quantum Gravity Theory Describing the Real State of the Universe [PDF]
, 2013 Tomasz Borowski
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Molecular Oncology, EarlyView.The 5th edition of the European Code Against Cancer (ECAC5) contains 14 recommendations on cancer prevention. Here, we update the cancer prevention recommendations regarding the use of hormone replacement therapy (HRT), which is positioned as recommendation number 13 of the ECAC5.
Mangesh A. Thorat +18 more
wiley +1 more source