Results 141 to 150 of about 1,423,214 (318)
No-Boundary Wave Functional and Own Mass of the Universe
UniverseAn alternative formulation of the no-boundary initial state of the universe in the Euclidean quantum theory of gravity is proposed. Unlike the no-boundary Hartle–Hawking wave function, in which time appears together with macroscopic space–time in the ...
Natalia Gorobey +2 more
doaj +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Felsefe Dünyası, 2005 Ömer ÖZDEN, AŞKIN (SEVGİNİN) GÜCÜ, FELSEFE DÜNYASI DERGİSİ, SAYI:42 ...
Ömer Özden
doaj
The Problem of Unity and Plurality in Teftâzânî
Din ve Bilim Muş Alparslan Üniversitesi İslami İlimler Fakültesi DergisiIn the religious texts of Muslims, some commands praise all forms of wisdom and emphasize the necessity of acquiring wisdom wherever it is found. For this reason, from the early periods, the Islamic intellectual movement made great efforts to become ...
Ekrem UĞURLU
doaj +1 more source
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
İlahiyat Akademi, 2016 En büyük kriz insanlık krizidir. Ekonomik, sosyal, siyasal ve kültürel krizler belki bir şekilde aşılabilir ama insanlık krizi tamiri kolay olmayan büyük yaralar açar. O nedenle en büyük yatırım insana yapılan yatırımdır.
Kadir Özköse
doaj
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Ankara Üniversitesi İlahiyat Fakültesi DergisiBu çalışmada, İbn Teymiyye’nin (ö. 728/1328) evrene matuf varlıklar zincirine verdiği hükmün, benimsediği “tüm” (kull) kavramıyla ilişkisi ele alınmıştır.
Cihan Özaykan
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