Results 81 to 90 of about 113,830 (296)

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

open access: yesFEBS Letters, EarlyView.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche   +2 more
wiley   +1 more source

“Tüm” (Kull) Kavramı ve Geçmişe Matuf Varlıklar Zincirine Dair Hükme Etkisi: İbn Teymiyye Metinleri Üzerinden Bir Okuma

open access: yesAnkara Üniversitesi İlahiyat Fakültesi Dergisi
Bu çalışmada, İbn Teymiyye’nin (ö. 728/1328) evrene matuf varlıklar zincirine verdiği hükmün, benimsediği “tüm” (kull) kavramıyla ilişkisi ele alınmıştır.
Cihan Özaykan
doaj   +1 more source

The Universe and Life [PDF]

open access: yesФилософия и космология, 2016
This article discusses some of the unsolved problems of modern cosmology, which lead to the need to consider the role of living matter in the evolution of the universe. The author proposes the hy- pothesis of the emergence, in the process of evolution of
Eduard Kazantsev
doaj  

A coiled‐coil domain triggers oligomerization of MmpL10, the mycobacterial transporter of trehalose polyphleate precursor

open access: yesFEBS Letters, EarlyView.
Most MmpLs transport lipids and glycolipids of the complex mycomembrane of mycobacteria. This study shows that MmpL10 from Mycobacterium smegmatis, the transporter of the trehalose polyphosphate precursor, harbors a coiled‐coil‐like extension. Biochemical and electron microscopy studies demonstrate that the coiled‐coil enables MmpL10 to trimerize.
Julie Couston   +7 more
wiley   +1 more source

The Hyperboloidal Universe

open access: yesSSRN Electronic Journal, 2022
This paper investigates a relativistic model of the Universe in which the geometry describes a 4D version of the 2-sheeted hyperboloid that is isotropic, homogeneous in space at a given time and inhomogeneous in time. The internal Schwarzschild metric is used for this model, which is justified by the fact that spherically-symmetric empty spaces in the ...
openaire   +1 more source

Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product

open access: yesMolecular Oncology, EarlyView.
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens   +8 more
wiley   +1 more source

The age of the universe [PDF]

open access: yesPhysics Reports, 1996
invited review presented at the 2nd UCLA conference on Sources and Detection of Dark Matter in the Universe, to appear in Nuclear Physics B Proceedings Supplement, 10 pages, uses espcrc2 ...
openaire   +5 more sources

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren   +16 more
wiley   +1 more source

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