ADMINISTRACIÓN Y PLANEACIÓN DEL NÚCLEO DE DESARROLLO EDUCATIVO, 1980
El texto que aquí reseñamos fue elaborado como material didáctico para la capacitación de los Directores y Supervisores de Núcleos de Desarrollo Educativo y demás funcionarios comprometidos en el programa.
Universidad del Valle Universidad del Valle
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Adenovirus-mediated suppression of hypothalamic glucokinase affects feeding behavior [PDF]
Glucokinase (GK), the hexokinase involved in glucosensing in pancreatic β-cells, is also expressed in arcuate nucleus (AN) neurons and hypothalamic tanycytes, the cells that surround the basal third ventricle (3V).
Barahona, María José+10 more
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Tucumanin, a β-hydroxy-γ-lactone bistetrahydrofuranic acetogenin from Annona cherimolia, is a potent inhibitor of mitochondrial complex I [PDF]
A new β-hydroxy-γ-methyl-γ-lactone bistetrahydrofuranic acetogenin, tucumanin, with the infrequent symmetrical threo/trans/threo/trans/ threo relative configuration at the tetrahydrofuran rings was isolated from Annona cherimolia (Annonaceae) seeds.
Alvarez, Olga+8 more
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Reversal of gastrointestinal carcinoma-induced immunosuppression and induction of antitumoural immunity by a combination of cyclophosphamide and gene transfer of IL-12 [PDF]
Immunotherapy-based strategies for gastrointestinal carcinomas (GIC) have been exploited so far, but these approaches have to face strong mechanisms of immune escape induced by tumours.
Alaniz+69 more
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El Excmo. Sr. Ministro de Educación Nacional, D. Jesús Rubio García-Mina, ha pronunciado en la Universidad de Granada, con motivo de la apertura de curso universitario, el discurso que, por su excepcional importancia, se publica a continuación: Universidad de Carolina.
openaire +2 more sources
Comment on “Bilaterian Burrows and Grazing Behavior at >585 Million Years Ago” [PDF]
Pecoits et al. (Reports, 29 June 2012, p. 1693) describe bilaterian trace fossils and assign them an Ediacaran age based on the age of a granite interpreted as intrusive.
Beri, Angeles+4 more
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Thyroid status modulates T lymphoma growth via cell cycle regulatory proteins and angiogenesis [PDF]
We have shown in vitro that thyroid hormones (THs) regulate the balance between proliferation and apoptosis of T lymphoma cells. The effects of THs on tumor development have been studied, but the results are still controversial.
Barreiro Arcos, María Laura+10 more
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ALMA observations of Elias 2–24: a protoplanetary disk with multiple gaps in the Ophiuchus molecular cloud [PDF]
We present ALMA 1.3 mm continuum observations at 0. 2 (25 au) resolution of Elias 2–24, one of the largest and brightest protoplanetary disks in the Ophiuchus Molecular Cloud, and we report the presence of three partially resolved concentric gaps located
Ansdell, Megan+23 more
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Fricke and polymer gel 2D dosimetry validation using Monte Carlo simulation [PDF]
Complexity in modern radiotherapy treatments demands advanced dosimetry systems for quality control. These systems must have several characteristics, such as high spatial resolution, tissue equivalence, three-dimensional resolution, and dose-integrating ...
Chacón Obando, D.+12 more
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Temporal and spatial expression of genes involved in DNA methylation during reproductive development of sexual and apomictic Eragrostis curvula [PDF]
Recent reports in model plant species have highlighted a role for DNA methylation pathways in the regulation of the somatic-to-reproductive transition in the ovule, suggesting that apomixis (asexual reproduction through seeds) likely relies on RdDM ...
Echenique, Carmen Viviana+9 more
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