Results 21 to 30 of about 308,817 (294)

Evolución de la intermediación turística en España tras la aparición de las TIC en el sector

Revista Empresa y Humanismo, 2017
En la década de los 90, Internet irrumpió con fuerza en el sector turístico español y las empresas del sector vieron este hecho con recelo. En especial, las agencias de viajes, que no pasaban por su mejor momento debido a la saturación del sector y el ...
Ainara Rodríguez-Zulaica, Ricardo Pastor, María Asunción Fernández-Villarán Ara   +2 more
doaj   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Smart Bandwidth Assignation in an Underlay Cellular Network for Internet of Vehicles

Sensors, 2017
The evolution of the IoT (Internet of Things) paradigm applied to new scenarios as VANETs (Vehicular Ad Hoc Networks) has gained momentum in recent years. Both academia and industry have triggered advanced studies in the IoV (Internet of Vehicles), which
Idoia de la Iglesia, Unai Hernandez-Jayo, Eneko Osaba, Roberto Carballedo   +3 more
doaj   +1 more source

Natural Language Processing Techniques for Text Classification of Biomedical Documents: A Systematic Review

Information, 2022
The classification of biomedical literature is engaged in a number of critical issues that physicians are expected to answer. In many cases, these issues are extremely difficult.
Cyrille YetuYetu Kesiku, Andrea Chaves-Villota, Begonya Garcia-Zapirain   +2 more
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

Unión de Universidades Latinoamericanas

, 1951
El Boletín Mural de la Unión de Universidades de América Latina y el Caribe fue una edición periódica que se publicó en una sola lámina plegable desde 1949 a 1952 en la Imprenta Universitaria, Guatemala C. A.
Unión de Universidades Latinoamericanas
core   +1 more source

Breve reseña histórica

Revista Digital de Políticas Lingüísticas, 2014
La Asociación de Universidades del Grupo Montevideo (AUGM) nace en agosto de 1991, y su período fundacional se extiende durante un año, época en que los Rectores de las Universidades pioneras que la componen, se unen en un Acta de Intención Fundacional ...
Asociación de Universidades Grupo Montevideo
doaj  

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source