Results 111 to 120 of about 21,093 (211)

PharmVar GeneFocus: CYP1A2—Clinical Impact, Genetic Variation, and Updated Nomenclature

Clinical Pharmacology &Therapeutics, EarlyView.
The Pharmacogene Variation Consortium (PharmVar) provides nomenclature for the highly polymorphic human CYP1A2 gene. CYP1A2 plays a crucial role in the biotransformation of several commonly used drugs, including antipsychotics, antidepressants, anxiolytics, and methylxanthines.
Katalin Monostory, Gonzalo Villapalos Garcia, Dora Koller, Solomon Adams, Chad A. Bousman, Evangelia Eirini Tsermpini, Michelle Whirl‐Carrillo, Amy J. Turner, Volker M. Lauschke, Mohamed Nagy, Erin C. Boone, Teri E. Klein, Pablo Zubiaur, Andrea Gaedigk   +13 more
wiley   +1 more source

Readiness and Maturity for a Smart Circular Economy to Enhance Sustainability Performance: A Multidimensional Framework for the Hospitality Sector

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Research on readiness and maturity for the smart circular economy (SCE) remains fragmented, especially in the hospitality sector. This study develops a multidimensional framework that integrates the principles of the circular economy, Industry 4.0, and sustainability performance in the context of tourist accommodations.
Rafael Mora‐Contreras, Paz Morer‐Camo, Marta Ormazabal, Carmen Jaca, Maria Isabel Rodriguez‐Ferradas, María Jesús Álvarez   +5 more
wiley   +1 more source

Do CSR Committees Pay Off? Direct and Indirect Links to Financial and ESG Performance

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Corporate boards increasingly delegate sustainability oversight to dedicated CSR committees, yet evidence on whether these committees improve corporate performance remains mixed. This study argues that part of this inconsistency arises because prior research often emphasizes overall associations between CSR committees and performance without ...
Ana Isabel Lopes
wiley   +1 more source

Elimination Profile of Deflazacort and Metabolites in Urine and Plasma Following Oral Administration: Relevance to Sports Drug Testing

Drug Testing and Analysis, EarlyView.
Results confirm that the MRL of 30 ng/mL for 21‐desacetyl‐deflazacort together with a 3‐day washout period is an appropriated strategy to detect oral deflazacort administration in sport competition. ABSTRACT Deflazacort (DEF) is a glucocorticoid prohibited in sports competitions when orally administered.
Sergi Coll, Claudia Bressan, Núria Monfort, Ana Aldea‐Perona, Marcel·lí Carbó, Rosa Ventura   +5 more
wiley   +1 more source

Biomarkers of lung congestion and injury in acute heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 781-789, April 2025.
Abstract Acute heart failure (AHF) classification and management are primarily based on lung congestion and/or hypoperfusion. The quantification of the vascular and tissue lung damage is not standard practice though biomarkers of lung injury may play a relevant role in this context.
Marco Guazzi, Gabriele Novello, Francesca Bursi, Anna Caretti, Noemi Furlotti, Ross Arena, Paola Argiento, Julio Núñez, Antoni Bayes‐Genis, Marco Metra   +9 more
wiley   +1 more source

[Prevalence of risk factors associated with physical fitness in university students: A cross-sectional study]. [PDF]

Aten Primaria
Rodríguez Cordero OJ, Polo Gallardo R, Terán Martínez MÁ, Vásquez Osorio FC.   +3 more
europepmc   +1 more source

Analysis of the usefulness and benefits of ultrafiltration in cardiorenal syndrome: A systematic review

ESC Heart Failure, Volume 12, Issue 2, Page 1194-1202, April 2025.
Abstract Aims Cardiac decompensation in cardiorenal syndrome (CRS) results in systemic congestion usually treated with diuretics. When despite high doses of diuretics, response is poor, ultrafiltration (UF) appears to be a useful and safe technique.
Borja Guerrero Cervera, Raquel López‐Vilella, Víctor Donoso Trenado, María Peris‐Fernández, Paula Carmona, Amparo Soldevila, Sergi Tormo, Ramón Devesa, María Jesús Montero Hernández, Luis Martínez Dolz, Julio Hernández Jaras, Pilar Sánchez‐Pérez, Luis Almenar‐Bonet   +12 more
wiley   +1 more source

Knowledge, attitudes, and practices regarding self-medication among Generation Z university students. [PDF]

Rev Esc Enferm USP
Silveira HNG, Secoli SR, Menezes AC, Sousa MM, Ferreira SSR, Oliveira F, Andrade SN, Trevisan DD.   +7 more
europepmc   +1 more source

Risk assessment using IEUBK model for the Naica mine tailings

Environmental Progress &Sustainable Energy, EarlyView.
Abstract Mexico has a long history of mineral extraction, during which limited environmental regulations allowed the accumulation of toxic waste near communities, primarily in rural or undeveloped areas. Some of these toxic substances, such as lead, pose significant risks to vulnerable populations, particularly children aged 0 to 7 years.
A. Contreras‐Guardiola, M. A. Olmos‐Márquez, L. Cortés‐Palacios, E. Santellano‐Estrada, M. C. Valles‐Aragón   +4 more
wiley   +1 more source

O hiato entre conhecimento sobre as vias de transmissão e as práticas de prevenção da AIDS entre estudantes da USP: a atuação das ideologias coletivas de defesa

Psicologia USP
Campanhas baseadas em resultados de pesquisas sobre comportamento que visam mudança comportamental são freqüentemente fadadas ao malogro. Provavelmente isso ocorre, entre outras razões, porque a ação humana é, em boa parte, regida por fatores ...
Arakcy Martins Rodrigues
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