Results 131 to 140 of about 21,271 (210)
Pediatric epilepsy surgery: Global survey of invasive explorations
Epilepsia, EarlyView.Abstract Objective
Invasive presurgical evaluation plays a key role in pediatric epilepsy surgery, particularly in magnetic resonance imaging (MRI)‐negative cases, by guiding resective, disconnective, or ablative procedures. This International League Against Epilepsy (ILAE) Pediatric Epilepsy Surgery Taskforce study provides an updated global overview ...Georgia Ramantani, Martha Feucht, Dorottya Cserpan, Javier Aparicio, Alexis Arzimanoglou, Fabrice Bartolomei, William Bingaman, Kees P. J. Braun, Richard J. Burman, Dezhi Cao, Roberto Caraballo, Mathilde Chipaux‐Raffo, Thomas Cloppenborg, J. Helen Cross, Arthur Cukiert, Cristine Mella Cukiert, Daniel J. Curry, Luca De Palma, Petia Dimova, Christin Eltze, Dario J. Englot, Johannes M. Nico Enslin, Aria Fallah, Stefano Francione, Deepak Gill, Tove Hallböök, A. Simon Harvey, Hans Holthausen, Sita Jayalakshmi, Yuwu Jiang, Lakshminarayanan Kannan, Matt Lallas, Sandeep Bhagwan Patil, María Ángeles Pérez‐Jiménez, Juan Carlos Pérez‐Poveda, Tom Pieper, Sabine Rona, Victoria San Antonio‐Arce, Jay Shetty, Mary Lou Smith, Piradee Suwanpakdee, Oana Tarta Arsene, Laura Tassi, Martin Tisdall, Manjari Tripathi, Ahsan Moosa Naduvil Valappil, Howard Weiner, Elaine Wirrell, Lixin Cai, Sarah Ferrand‐Sorbets, ILAE Pediatric Epilepsy Surgery Taskforce and Study Group, Carmen Barba, Marcelo Budke, James Butler, Poodipedi Sarat Chandra, Mary Connoly, Sameer Dal, Georg Dorfmüller, Noelle Enright, Siby Gopinath, Aris Hadjinicolaou, Masaki Iwasaki, Thilo Kalbhenn, Kalman A. Katlowitz, Kensuke Kawai, Takayuki Kikuchi, Katarzyna Kotulska‐Jóźwiak, Niklaus Krayenbühl, Martin Kudr, Noritsugu Kunihiro, Cassia Maniquis, Ailsa McLellan, Carolina Munoz Castro, Lino Nobili, Wim Otte, Manas Panigrahi, Veronica Pelliccia, Karl Rössler, Siraruj Sakoolnamarka, Didier Scavarda, Catalina Soto Órdenes, Nicola Specchio, Nigel Peter Symss, TS Dhanya, Olga Teo, Hartlieb Till, Dilşad Türkdoğan, Takehiro Uda, Vrajesh Udani, Shimrit Uliel‐Sibony, Naotaka Usui, Carlos Valera, Lejla Vendegh, Yi Wang, Jithangi Wanigasinghe, Jo Wilmshurst, Oscar Zorro Guio +96 morewiley +1 more sourceDiagnosis and management guidelines for infantile epileptic spasms syndrome around the world: A scoping review and comparative study of international approaches
Epilepsia, EarlyView.Abstract Objective
Infantile epileptic spasms syndrome (IESS) is an epileptic encephalopathy requiring rapid diagnosis and treatment to optimize neurodevelopmental outcomes. Although multiple national and regional guidelines exist, recommendations vary.Gozde Erdemir, Chethan K. Rao, Anne Francine Pino, Christina Briscoe, Debopam Samanta, Jo M. Wilmshurst, Sonal Bhatia, Jessica L. Carpenter, Christina Hoei‐Hansen, Puneet Jain, Tommy Stodberg, Robyn Whitney, Ryuki Matsuura, Karina Rosso Astorga, Keryma Acevedo Gallinato, Pratibha Singhi, Aristides Hadijinicolaou, Gia Melikishvili, Patricia Smeyers, Nicola Specchio, Stéphane Auvin, Pediatric Epilepsy Research Consortium Infantile Spasm Work Group and International Committee +21 morewiley +1 more sourceEffectiveness and tolerability of fenfluramine in pediatric and adult patients with developmental and epileptic encephalopathies: A multicenter, retrospective, real‐world clinical‐practice study
Epilepsia, EarlyView.Abstract Objective
Developmental and epileptic encephalopathies (DEEs) are characterized by drug‐resistant seizures and developmental slowing/regression. We examined the efficacy and tolerability of fenfluramine (FFA) in pediatric and adult patients with Lennox–Gastaut syndrome (LGS), Dravet syndrome (DS), and other DEEs.Vicente Villanueva, Elena González‐Alguacil, Patricia Smeyers, Sara Hernández, Victor Soto‐Insuga, Alejandro Fernández‐Cabrera, Laura Olivié, Teresa de Santos, Beatriz Parejo, Lucas Iacampo, Belén Ortuño, Javier Aparicio, Montserrat Fuentes, Juan Rodriguez‐Uranga, Paula Martínez‐Agredano, José Carlos Estévez, Angel Aledo‐Serrano, Rocio Martin‐Alvarez, David Conejo, Belen Baena, Blanca Mercedes‐Álvarez, Yolanda López, Alba Sierra‐Marcos, Rocio Trincado‐Lamuño, Mouna Ennazeh, Jesús González de la Aleja, Julia Renau, Maria Dolores Castro‐Vilanova, Fátima Romero‐Aguilera, José M. Serratosa +29 morewiley +1 more sourceProlonged fenfluramine use in open‐label studies of Dravet or Lennox–Gastaut syndromes: Long‐term safety, tolerability, patient global functioning, and considerations for interpreting effectiveness
Epilepsia, EarlyView.This graphical abstract provides an overview of the content from this open‐label extension study of fenfluramine use in patients with Dravet syndrome or Lennox‐Gastaut syndrome. Abstract Objective
Long‐term safety and global functioning are reported in patients with Dravet syndrome (DS) or Lennox–Gastaut syndrome (LGS) treated with fenfluramine in an ...Antonio Gil‐Nagel, Kelly G. Knupp, Boudewijn Gunning, Domenica Immacolata Battaglia, Elizabeth A. Thiele, Ingrid E. Scheffer, An‐Sofie Schoonjans, Rima Nabbout, Nathalie Villeneuve, Kerstin Alexandra Klotz, Nicola Specchio, Rocio Sanchez‐Carpintero, Marta Zolnowska, Anne‐Liv Schulz, Lily Perrin, Najla Dickson, Mélanie Langlois, Amélie Lothe, Joseph Sullivan +18 morewiley +1 more sourceRefining diagnostic boundaries and electroclinical profiles of Lennox–Gastaut syndrome through unsupervised clustering
Epilepsia, EarlyView.Abstract Objective
Lennox–Gastaut syndrome (LGS) is a developmental and epileptic encephalopathy defined by polymorphic seizures, intellectual disability (ID), and characteristic electroencephalographic (EEG) patterns. The applicability and biological validity of current electroclinical criteria remain debated.Emanuele Cerulli Irelli, Marco Perulli, Maria S. Borioni, Anna Falco, Adolfo Mazzeo, Enrico Cocchi, Maria L. Gambardella, Alessandra Morano, Michela Quintiliani, Maria Picilli, Anna T. Giallonardo, Carlo Di Bonaventura, Domenica I. Battaglia +12 morewiley +1 more sourceFrom first seizure to specific antiseizure medication in Dravet syndrome: Quantifying delays in the DS'coverED study
Epilepsia Open, EarlyView.Abstract Objective
Dravet syndrome (DS) is a rare early‐onset developmental and epileptic encephalopathy with persistent delays between seizure onset and diagnosis. The DS'coverED study aimed to characterize current diagnostic timelines by examining each step and its duration, identifying residual barriers, and actionable solutions to optimize the ...Loucas Christodoulou, Maria Ballarà Petitbò, Sergio Aguilera Albesa, Simona Borroni, Perrine Hugon, Ratna Kumar, Tullio Messana, Pierre Meyer, Frédéric Villéga, Kerstin A. Klotz +9 morewiley +1 more source
