Results 91 to 100 of about 546,154 (304)

Safety and Effectiveness of Sutimlimab in Cold Agglutinin Disease: A Real‐World International Experience

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Sutimlimab is a monoclonal antibody against complement fraction C1s approved for the treatment of hemolytic anemia due to cold agglutinin disease (CAD). Here, we analyzed and report the largest international CAD cohort of sutimlimab‐treated patients ever reported to highlight its safety and effectiveness in the real‐world setting. We accrued a
Bruno Fattizzo   +38 more
wiley   +1 more source

Hereditary breast and ovarian cancer in Andalusian families: a genetic population study

open access: yesBMC Cancer, 2018
Background The BRCA1/2 mutation profile varies in Spain according to the geographical area studied. The mutational profile of BRCA1/2 in families at risk for hereditary breast and ovarian cancer has not so far been reported in Andalusia (southern Spain).
Bella Pajares   +11 more
doaj   +1 more source

Real‐World Outcomes of FLAG‐Ida Regimen in 1079 Adult Patients With First Relapsed/Refractory AML: A PETHEMA Study

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT In a large multicenter real‐world cohort, we aimed to evaluate outcomes of FLAG‐Ida salvage therapy for relapsed/refractory (R/R) acute myeloid leukemia (AML) and validated the SALFLAGE prognostic score. We analyzed 1079 adults with R/R AML treated across 112 PETHEMA institutions over 26 years (1998–2024), including patients with primary ...
Gaspar Aspas Requena   +49 more
wiley   +1 more source

Autoestima en jóvenes universitarios [PDF]

open access: yes, 2003
A partir de una muestra de 422 alumnos, divididos en tres grupos, se estudió la autoestima en jóvenes universitarios. Los resultados conducen a reflexionar acerca de la necesidad de integrar en la formación del psicólogo, alguna forma de asesoría ...
GONZALEZ ARRATIA LOPEZ FUENTES, NORMA IVONNE   +1 more
core  

Rationale of New Grading System: Central Compartment Atopic Disease

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Central compartment atopic disease (CCAD) has recently been recognized as a distinct phenotype within the spectrum of type 2–dominant chronic rhinosinusitis (CRS). Although international guidelines highlight polypoid changes in the central nasal cavity, standardized diagnostic and classification criteria are still lacking.
Ramón Moreno‐Luna   +11 more
wiley   +1 more source

Development and content validity of the evaluation of multidimensional functioning and risks in aging scale [PDF]

open access: yesPeerJ
Introduction Rising life expectancy has led to an increased prevalence of age-related conditions such as pain, dementia, and falls. To address these challenges, healthcare systems require efficient tools to identify which health domains are preserved or ...
José Fierro-Marrero   +4 more
doaj   +2 more sources

Metformin enhances external urethral sphincter integrity and restores continence via AMPK activation in a rat model of stress urinary incontinence

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The pathogenesis of stress urinary incontinence (SUI) is intimately associated with injury to the external urethral sphincter (EUS). In this study, we established an SUI model induced by double vaginal distension and demonstrated that metformin treatment activated the AMPK signaling in the EUS tissue.
Yuting Xu   +7 more
wiley   +1 more source

Pinceladas [PDF]

open access: yes, 2016
Quiero expresar mi agradecimiento a los responsables de la Revista Universidad, Ética y Derechos, RUED@ - puesta en marcha por la Conferencia Española de Defensores Universitarios (CEDU) en 2015 - por la distinción que supone colaborar en la ...
Sánchez Giralda, Tomás
core   +2 more sources

Relapses, Comorbidities, and Predictors of Outcome in Anti‐GABAA Receptor Encephalitis

open access: yesAnnals of Neurology, EarlyView.
Objectives To characterize the magnetic resonance imaging (MRI) lesion dynamics, comorbidities, predictors of relapse, and outcomes in anti‐γ‐aminobutyric acid type A receptor (GABAAR) encephalitis, and assess the utility of LIM‐domain‐only‐protein 5 (LMO5) antibodies as tumor markers.
Claudia Papi   +33 more
wiley   +1 more source

La mirada latina sobre la psicología positiva [PDF]

open access: yes, 2013
El siguiente trabajo intenta mostrar el avance que presenta Latinoamérica en cuanto al estudio y aplicación de temáticas relacionadas con la Psicología Positiva (PP).
Castro Solano, Alejandro   +1 more
core  

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