Results 111 to 120 of about 22,073 (258)

UGT1A1 genotype testing for irinotecan: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, EarlyView.
Abstract Irinotecan, a topoisomerase I inhibitor, is available as both non‐pegylated and pegylated formulations. The non‐pegylated formulation is licensed for use in advanced colorectal cancer either in combination with other agents or as monotherapy.
Dharmisha Chauhan, Cinzia Dello Russo, Jack Thompson, Dyfrig A. Hughes, Katherine Payne, Maria Tsakiroglou, Paul Ross, Rena Chauhan, Simon Jenkinson, Jessica Keen, Sophie Harding, Eleanor Lau, Michael Braun, Roshan Agarwal, Richard Adams, Elisabeth Rolf, Farah Al‐Sheikhli, Sarah Mitchell, Ruth Hammond, Rosie Roberts, Lorna Cairns, Shirley Heggarty, Janet Graham, Justin Mencel, Munir Pirmohamed   +24 more
wiley   +1 more source

MT‐RNR1 genotype testing for preventing aminoglycoside‐mediated ototoxicity: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, EarlyView.
Aminoglycosides are broad‐spectrum antibiotics used in the management of severe infections. Aminoglycosides are associated with nephrotoxicity and ototoxicity. Although dosing strategies such as once‐daily administration and therapeutic drug monitoring have reduced the incidence of nephrotoxicity, ototoxicity remains unpredictable and may occur at ...
John H. McDermott, Sian Hilton, Cinzia Dello Russo, Nicola Booth, Simon Drysdale, Philip Howard, Stephen Hughes, Mallinath Chakraborty, Helen McDevitt, Charlotte Alston, Maya Desai, Mike Beadsworth, Adam Reynolds, Serim Min, Katherine Payne, Munir Pirmohamed, William G. Newman   +16 more
wiley   +1 more source

Validation of the ABL + DT model: An ecosystemic framework for integrating arts and digital technologies in primary education

British Educational Research Journal, EarlyView.
Abstract Primary education teachers face increasing challenges in engaging diverse learners and fostering creativity, digital competence and other transversal skills, often lacking clear, practical guidance for integrating these skills into their classrooms.
Nella Escala, Montse Guitert, Teresa Romeu   +2 more
wiley   +1 more source

Informe universitario

, 2023
A pesar de que el informe sobre las universidades colombianas se publicó en la revista "Semana" a principios del año, todavía a esta hora, en este momento, sigue causando la mayor inquietud por injusto, por centralista, por descentralizado y por mentiroso.
openaire   +1 more source

Carrion ecology: concepts, interdisciplinary synthesis, and perspectives

Biological Reviews, EarlyView.
ABSTRACT Carrion is a ubiquitous resource in both terrestrial and aquatic ecosystems, yet it has long been overlooked in ecological research. Over the past two decades, studies on carrion and the many organisms that exploit it have flourished, revealing not only wide‐ranging ecological functions but also significance far beyond ecology.
Marcos Moleón, José A. Sánchez‐Zapata, Travis L. DeVault, Wayne M. Getz, Zebensui Morales‐Reyes, Daniel Redondo‐Gómez, Lara Naves‐Alegre, Solange A. Batista‐Nunes, Esther Sebastián‐González, Juan M. Pérez‐García, Kelly A. Waters, Thijs van Overveld, Craig Smith, Nuria Selva, Thomas A. Schlacher, Graeme Ruxton, Jesús Rodríguez, Martina‐M. Quaggiotto, Paula L. Perrig, Norman Owen‐Smith, Thomas M. Newsome, Isabel Navas, Yoshihiro Nakashima, Ana Mateos, Carlos Martínez‐Carrasco, Daniel Martín‐Vega, Berta Martín‐López, Antoni Margalida, Sergio A. Lambertucci, Adam Kane, Kevin Healy, Akane Hashizume, Antonio J. García‐Fernández, José A. Donázar, M. Eric Benbow, James C. Beasley, Philip S. Barton, Kathleen A. Alexander, Eneko Arrondo   +38 more
wiley   +1 more source

Panorama universitario

, 1982
Universidad Nacional de La ...
openaire   +1 more source

Technological Turbulence, Circular Economy Practices, and Digitalization as Determinants of Innovative Culture in High‐Growth Firms

Business Strategy and the Environment, EarlyView.
ABSTRACT In a business environment characterized by technological turbulence and an increasing societal demand for greater sustainability, companies seeking to enhance their growth are compelled to foster organizational cultures that promote continuous innovation.
José Bocoya‐Maline, Salustiano Martínez‐Fierro, José Aurelio Medina‐Garrido   +2 more
wiley   +1 more source

Sound Financial Practices and Entrepreneurs' Socio‐Environmental Commitment: Revealing the Role of Financial Barriers

Business Strategy and the Environment, EarlyView.
ABSTRACT Small enterprises (SEs) constitute a major component of economic systems, and their socio‐environmental commitment is critical for promoting societal well‐being. This paper examines the direct effect of sound financial practices on socio‐environmental commitment and evaluates the mediating role of financial constraints—specifically debt and ...
Marcos Álvarez‐Espiño, Sara Fernández‐López, Lucía Rey‐Ares   +2 more
wiley   +1 more source

Corporate Decarbonization: Understanding CO2 Emission Drivers Across High‐ and Low‐Polluting Firms in OECD Countries

Business Strategy and the Environment, EarlyView.
ABSTRACT Decarbonization of the economy is a central challenge in the fight against climate change. Although most governments show clear commitment to limiting global warming, the drivers of corporate decarbonization remain underexplored. Using a dataset of 1052 firms from OECD, this article analyses how intangible assets and environmental innovation ...
Yanik Nimtz, Mercedes Teruel
wiley   +1 more source

[Prevalence of risk factors associated with physical fitness in university students: A cross-sectional study]. [PDF]

Aten Primaria
Rodríguez Cordero OJ, Polo Gallardo R, Terán Martínez MÁ, Vásquez Osorio FC.   +3 more
europepmc   +1 more source