Results 41 to 50 of about 34,731 (302)

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

L’ensenyament de les doctrines de Ramon Llull a les escoles i universitats europees durant l’època moderna

Educació i Història: Revista d'Història de l'Educació, 2016
El present article intenta mostrar com l’ensenyament de les doctrines de Ramon Llull va estar present en els debats universitaris i escolars durant l’època moderna a Europa. Des del segle xvi fins al segle xviii, el pensament de Ramon Llull va tenir una
Rafael Ramis Barceló
doaj  

Glutamate in Pyridoxine-Dependent Epilepsy

Pediatric Neurology Briefs, 1994
Cerebrospinal fluid levels of glutamate, g-aminobutyric acid, and pyridoxal-5-phosphate examined in a patient with pyridoxine dependency while on and off vitamin B6 treatment are reported from Universitat Munchen, and Universitats-Nervenklinik, Wurzburg,
J Gordon Millichap
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

L'avaluació de l'alumnat a la universitat Universitat de Barcelona

, 2001
The main aim of this article is to explore the relationships between the two primary activities in higher education institutions: teaching and research. This task could be done from different perspectives. Due to opportunity and interest reasons I have focused the content of this article in two broad and complementary issues.
Bordas, Inmaculada, Cabrera, Flor
openaire   +5 more sources

Ressenya de llibre: Rué Domingo, J. (2009) Un model d’anàlisi de la qualitat de l’ensenyament des de la perspectiva dels estudiants a titulacions de quatre universitats catalanes (UAB; UB; UPC; URV). AQU: Barcelona.

Revista d'Innovació i Recerca en Educació, 2010
Ressenya del llibre de Rué Domingo, J. (2009) Un model d’anàlisi de la qualitat de l’ensenyament des de la perspectiva dels estudiants a titulacions de quatre universitats catalanes (UAB; UB; UPC; URV). AQU: Barcelona.
Anna Forés Miravalles
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Congenital Hydrocephalus

Pediatric Neurology Briefs, 1988
Intrauterine intraventricular hemorrhage occurring about 2 weeks or more prior to birth was the cause of congenital hydrocephalus in 4 newborn infants reported from the Abteilung Neonatologie, Universitats-Kinderklinik, Rumelin-strasse 23; D-7400 ...
J Gordon Millichap
doaj   +1 more source

Pompeu Fabra, a la Universitat i de la Universitat

, 2020
ompeu Fabra és l’arquitecte de la codificació moderna de la llengua catalana: la seva proposta normativa ha esdevingut el model que guia la tasca prescriptiva actual. Però aquest paper de codificador és només una de les cares d’una personalitat molt més complexa, que comprèn les facetes de lingüista autodidacte, de docent i gestor universitari, i de ...
Murgades, Josep, 1951-, Nogué Serrano, Neus, Bellés, Eloi   +2 more
openaire   +2 more sources