Results 211 to 220 of about 94,324,018 (312)

Current Practice in the Diagnosis and Management of <i>Mycoplasma pneumoniae</i> Infections: A Survey of Korean Physicians in 2024. [PDF]

J Korean Med Sci
Choe YJ, Yang HJ, Lee JK, Cho HK, Sung H, Jang GC, Yoo IY, Eun BW, Choi SH, Kwak BO, Kim HS, Lee E, Kim K, Yang EA, Yoon SH, Lee B, Lee JY, Kim YJ.   +17 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Strengthening Preventive Care for Culturally and Linguistically Diverse People in Australia: The Case for Community Health Worker Programs. [PDF]

Health Promot J Austr
Mistry SK, Yadav UN, Bhaumik S, Lassi ZS, Harris M.   +4 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Evaluation of the Correlation of Calprotectin and SES-CD Score at the Time of Diagnosis and Follow-up After Diagnosis in Pediatric Patients With Crohn's Disease in Korea. [PDF]

J Korean Med Sci
Kwon Y, Kim SH, Lee YM, Kim ES, Lee EH, Choi S, Choe BH, Jang HJ, Jeong IS, Kim J, Yi DY, Kim SC, Lee YJ, Choi SY, Lee Y, Choe YH, Kang B.   +16 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Empirical Meropenem Versus Piperacillin/Tazobactam for Critically Ill Adults With Sepsis: Feasibility of a Randomised Trial. [PDF]

Acta Anaesthesiol Scand
Meier NF, Møller MH, Kjær MN, Sjövall F, Munch MW, Kaas-Hansen BS, Thorsen-Meyer HC, Rasmussen BS, Helleberg M, Hertz FB, Lange T, Jensen AKG, Andersen LW, Andersen JS, Michelsen J, Andersen LPK, Bestle MH, Brøchner AC, Itenov TS, Christensen S, Plovsing RTR, Koch KU, Møller A, Schjørring OL, Cranø NB, Vamdrup-Andersen K, Placido D, Meyhoff TS, Anthon CT, Tøgern A, Grigonyte-Daraskeviciene M, Engbakken Z, Kamstrup AW, Uhre KR, Barakji JA, Larsen RF, Perner A, Granholm A.   +37 more
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Author Correction: Influence of protein aggregates, extracellular vesicles, and lipoprotein fusion on ionizable lipid nanoparticles protein corona analysis. [PDF]

Nat Commun
Borhan B, Murray AM, Saei AA, Ghaffari B, Jackson JE, Mohammed N, Mitchell MJ, Vali H, Whitehead KA, Mahmoudi M.   +9 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source