KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Se presenta la experiencia de "tutoría entre pares", desarrollada en una universidad de Bucaramanga, Colombia, con el propósito de crear condiciones y escenarios deformación universitaria que permitan autorregular los aprendizajes e incorporar nuevas ...
Claudia Esperanza Cardozo-Ortiz
doaj
Describing consumer involvement, recruitment, retention in Australian occupational therapy university education: A cross sectional survey. [PDF]
Soon YE +3 more
europepmc +1 more source
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
En este artículo se exponen los resultados de un proceso de investigación desarrollado con el objetivo de comprender el lugar de la ironía en el aula universitaria mediante un estudio de tipo cualitativo instalado en el paradigma interpretativo ...
Flor Adelia Torres-Hernández
doaj
Trends in education during the pandemic: modern online technologies as a tool for the sustainability of university education in the field of media and communication studies. [PDF]
Hurajova A, Kollarova D, Huraj L.
europepmc +1 more source
NKCC1: A key regulator of glioblastoma progression
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Self-reported critical gaps in the essential knowledge and capacity of spatial epidemiology between the current university education and competency-oriented professional demands in preparing for a future pandemic among public health postgraduates in China: a nationwide cross-sectional survey. [PDF]
Lan T +7 more
europepmc +1 more source

