Results 81 to 90 of about 1,177,514 (265)

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

A User-Centric Smart Library System: IoT-Driven Environmental Monitoring and ML-Based Optimization with Future Fog–Cloud Architecture

Applied Sciences
University libraries are essential academic spaces, yet existing smart systems often overlook user perception in environmental optimization. A key challenge is the lack of adaptive frameworks balancing objective sensor data with subjective user ...
Sarkan Mammadov, Enver Kucukkulahli
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

FEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey, Vaishnavi Sanjayan, Praveen Singh, Shantanu Sengupta, Anand Kumar Bachhawat   +4 more
wiley   +1 more source

Bibliotecas universitarias y automatización: un panorama de la Ciudad de México

Revista Interamericana de Bibliotecología, 2011
Después de contextualizar la educación superior en México, se ofrece un panorama de las condiciones de automatización de las bibliotecas universitarias en su Área Metropolitana, especialmente en lo que tiene que ver con el Sistema Integral de ...
Oscar Arriola Navarrete, Graciela Tecuatl Quechol   +1 more
doaj  

Sources of Up-to-Date Information of the University Library during the Full-Scale Russian Invasion of Ukraine

University Library at a New Stage of Social Communications Development
Objective. The article aims to highlight the peculiarities of the acquisition process of a university research library in wartime and the qualitative satisfaction of readers' requests with the help of stock collections.
L. M. LUCHKA
doaj   +1 more source

Universities and University Libraries in Turkey

LIBER Quarterly: The Journal of the Association of European Research Libraries, 2008
This article draws a picture of the education system and library environment in Turkey. It starts off with a brief overview of the Turkish education system and the proportion of the population involved in formal and informal education. As 44% of the Turkish population is under 25, there is a big demand for higher education in Turkey. This demand drives
openaire   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Preservation of the results of scientific, pedagogical and research experience in RUDN University information products

RUDN Journal of Informatization in Education
Problem statement. The educational and scientific status of universities is largely reflected in the results of the publication activities of teachers, researchers, and students.
Elena Yu. Lotova
doaj   +1 more source