Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Sistema de gestão para biblioteca universitária (SGBU)
Baseando-se na importância da Biblioteca Universitária para o processo educacional, e tendo a sua excelência administrativa como um dos pressupostos para atender satisfatoriamente às necessidades dos usuários, a autora pretende fornecer subsídios que ...
Cibele Vasconcelos Dziekaniak
doaj
University Library as an object of evaluation
The problem of evaluating the activity of university libraries is studied. Different periods of library statistics development are considered. The conclusions on the necessity to review some of the evaluation criteria in connection with the recent ...
E. N. Opekunova
doaj
Formes de réception et d’appropriation des ressources numériques en milieu étudiant.
An ethnographical inquiry on the users of the university library of the University of Toulouse (France, literature and human sciences) carried out in 2007-2008 shows how students do with the Web environment and electronical resources.
Mariangela Roselli
doaj +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Use of Library Catalogue in Nigerian University Libraries: A Focus on Redeemer’s University Library
The library as a service oriented organization is expected to provide the bibliographic resources and services channeled towards the fulfillment of its parent institution’s goals and objectives. The library ensures that the resources so provided are well organized to allow easy access by the library users.
openaire +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
University Libraries in Türkiye: Past to Present - A Comprehensive Analysis
University libraries play a vital role in the academic landscape by providing a wide range of essential support and services to their members. From research materials and academic resources to access to cutting-edge technology and expert staff, these ...
Güler Demir, Hasan Sacit Keseroğlu
doaj +1 more source
Development of a Smartphone-Based University Library Navigation and Information Service Employing Wi-Fi Location Fingerprinting. [PDF]
Retscher G, Leb A.
europepmc +1 more source

