Results 121 to 130 of about 70,601 (254)

Directed evolution of novel AAV capsids for enhanced delivery to mouse and human Schwann cells. [PDF]

Mol Ther Nucleic Acids
Carneiro AD, Nisanov AM, Lee H, Schaffer DV.   +3 more
europepmc   +1 more source

RNA Helicase DDX21 Controls CD4+ T Cell Proliferation and Promotes Inflammatory Bowel Disease via Translational Control

Advanced Science, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD) is characterized by dysregulated T cell responses. RNA helicases, including DExD‐box helicase 21 (DDX21), are pivotal in RNA metabolism, but their role in T cell‐mediated pathology during IBD remains unclear. Here, we demonstrate that DDX21 expression in CD4+ T cells correlates with cell cycle and translation ...
Yujuan Zhang, Chen Kan, Xinhui Yang, Yajuan Hao, Xuemin Cai, Mei Yang, Qianqian Zhang, Zhengting Wang, Ning Jiang, Lei Wang, Hua‐Bing Li, Jing Zhou   +11 more
wiley   +1 more source

Reference genome of an irruptive migrant, the pine siskin (Spinus pinus). [PDF]

J Hered
Cortez J, Slade JWG, Van Laar TA.
europepmc   +1 more source

A 3D Human Bone and Bone Marrow‐on‐a‐Chip Model for In Vitro Bone Remodeling and Immune Cell Maintenance

Advanced Science, EarlyView.
This study presents a human Bone (and Bone Marrow)‐on‐a‐Chip model based on native human bone scaffolds and autologous cells. Dynamic perfusion and sequential cell seeding replicate the physiological bone remodeling process in vitro, enabling the long‐term culture of functional, mature bone marrow immune subpopulations.
Nina Stelzer, Melanie‐Jasmin Ort, Kristian Händler, Emely Bortel, Ioanna Maria Dimitriou, Martin Textor, Georg N. Duda, Janosch Schoon, Uwe Marx, Uwe Kornak, Annika Winter, Bernhard Hesse, Stefanie Donner, Sebastian Hardt, Oliver Klein, Simon Reinke, Malte Spielmann, Sven Geißler   +17 more
wiley   +1 more source

A reference genome for Colusa grass, Neostapfia colusana, a threatened and endangered California vernal pool plant. [PDF]

J Hered
Pennington LK, Escalona M, J Toews D, Chumchim N, Cooper R, Fairbairn CW, Marimuthu MPA, Miller C, Nguyen OH, Ruiz-Ramos D, Seligmann WE, Stephens M, Toffelmier E, Shaffer HB, Meyer RS, Sexton JP.   +15 more
europepmc   +1 more source

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

Advanced Science, EarlyView.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu, Hongjie Dai, Xiaocui Zhong, Qibin Li, Hui Yuan, Yang Yang, Daiyong Huang, Lei Zhang, Rui Ran, Tian He, Yuanzhi Huang, Silas Villas‐Boas, Sergey Tumanov, Richard D. Cannon, Boris Novakovic, Richard Saffery, Yuhao Zhang, Xiaojing Dong, Ting‐Li Han   +18 more
wiley   +1 more source

The Selectivity Implications of Docking Libraries with Greater and Lesser Similarities to Bio-like Molecules. [PDF]

J Med Chem
Hall BW, Sakamoto K, Huang XP, Irwin JJ, Shoichet BK, Roth BL.   +5 more
europepmc   +1 more source

Annual Reports of the Libraries of the University of California. 1954-1958

, 1955
This document contains four annual reports: Annual Report  of the Libraries of the University of California1954-55Issued by the Library CouncilAnnual Report of the Libraries of the University of California1955-56Issued by the Library CouncilExpansion & Change:Annual Report of the Libraries of the University of California1956 ...
openaire   +1 more source

Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties

Advanced Science, EarlyView.
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez, Rose E. Presby, Sara Nakanishi, Pallavi Gaur, Ugur Akcan, Johannes Daugaard Krog, Iben Daugaard Krog, Lipi Das, David S. Johnson, Danny Jamoul, Douglas Jury, Brian Lawson, Jacob Körbelin, Lewis M. Brown, Vilas Menon, Dritan Agalliu, Irene Munk Pedersen   +16 more
wiley   +1 more source

A high-quality reference genome for the ornate shrew (Sorex ornatus). [PDF]

J Hered
Linn IJ, Escalona M, Nguyen O, Marimuthu MPA, Chumchim N, Fairbairn CW, Seligmann W, Beraut E, Conroy CJ, Bowie RCK, Nachman MW.   +10 more
europepmc   +1 more source