Results 51 to 60 of about 399,066 (305)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Embedding the Library into Scientific and Scholarly Communication through Knowledge Management [PDF]

, 1992
Knowledge management is a new role for academic research libraries that has the potential to integrate the library into scholarly and scientific communication in a significant way.
Lucier, Richard E.
core  

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Read & Let Read: An Alternative to the Transformative Agreement

Journal of Librarianship and Scholarly Communication, 2021
In March 2021, the University of California (UC) and Elsevier announced a new so-called “transformative agreement” that included slightly discounted article processing charges as UC’s route to open access in Elsevier journals.
Arthur Jason Boston
doaj   +2 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Collection Management Strategies in a Digital Environment.

Issues in Science and Technology Librarianship, 2001
This paper describes a grant-funded research project to relocate selected print journal runs, for which an electronic version is available, to remote storage from the shelves of campus libraries at the University of California. During the project, users
Cecily Johns
doaj   +1 more source

How to Make Friends and Influence Students [PDF]

, 2014
Presented at the California Academic & Research Libraries 2014 ConferenceGiven the widespread adoption of social media on the University of San Diego’s (USD) campus, Copley Library formed a Social Media Committee to manage the library’s social media ...
Burgert, Lisa, Nann, Alejandra, Sterling, Lorelei   +2 more
core  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

FARMs: A Geospatial Crop Modeling and Agricultural Water Management System

ISPRS International Journal of Geo-Information, 2021
To ensure agricultural sustainability and desirable environmental outcomes, stakeholders need systems-based model-driven decision support tools. The objective of this study was to develop a global scale web-based geospatial crop modeling application ...
Jae Sung Kim, Isaya Kisekka
doaj   +1 more source

Come together: A common vocabulary for University of California library homepages

College & Research Libraries News, 2011
ACRL TechConnect Susan Mikkelsen, Kristine Ferry, Rachael Hu, Brian Mathews, Deborah A. Murphy Come together A common vocabulary for University of California library homepages A cademic library Web sites are complex mixes of information gateways and links to resources and services.
Murphy, Deborah A., Mikkelsen, Susan, Ferry, Kristine, Hu, Rachael, Mathew, Brian   +4 more
openaire   +3 more sources