Results 81 to 90 of about 187,442,915 (279)

Diagnostic Classification Models for Ordinal Item Responses

Frontiers in Psychology, 2018
The purpose of this study is to develop and evaluate two diagnostic classification models (DCMs) for scoring ordinal item data. We first applied the proposed models to an operational dataset and compared their performance to an epitome of current ...
Ren Liu, Zhehan Jiang
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

End of Term Presidential Harvest 2016

, 2016
This is the collection for the End of Term Presidential Harvest 2016, an effort by the Library of Congress, the California Digital Library, the University of North Texas Libraries, the Internet Archive, George Washington University Libraries, Stanford ...
University of North Texas. Libraries.
core  

Assessing the Fitness of an Academic Library for Doctoral Research

Evidence Based Library and Information Practice, 2014
Objective – At the University of California, Berkeley (UCB), researchers compared how well the library collections supported doctoral research in the three related disciplines of education, psychology, and social welfare. The goal of this project was to
Susan Edwards, Lynn Jones
doaj  

Come together: A common vocabulary for University of California library homepages

College & Research Libraries News, 2011
ACRL TechConnect Susan Mikkelsen, Kristine Ferry, Rachael Hu, Brian Mathews, Deborah A. Murphy Come together A common vocabulary for University of California library homepages A cademic library Web sites are complex mixes of information gateways and links to resources and services.
Murphy, Deborah A., Mikkelsen, Susan, Ferry, Kristine, Hu, Rachael, Mathew, Brian   +4 more
openaire   +3 more sources

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Phase 3 Final Public Report [PDF]

, 2020
To conclude phase 3 reporting, the Systemwide Integrated Library System (SILS) Working Group shared this final report with the University of California (UC) Direction and Oversight Committee (DOC) and Council of University Librarians (CoUL) on July 27 ...
University of California Libraries
core   +1 more source