Results 51 to 60 of about 332,918 (306)
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
WHEN RANKINGS BECOME THE GOAL: ANALYSIS OF GOODHART'S LAW IN THE RANKING OF UNIVERSITIES IN VIETNAM
Tạp chí Khoa họcGoodhart's Law describes the phenomenon where a measure becomes a target, leading to behaviors aimed at optimizing that measure rather than achieving the true underlying goals.
Nguyen Phuc Quan
doaj +1 more source
Mesure et Évaluation en Éducation, 2007 Le présent article décrit les fondements de la formule de conversion des cotes de rendement au collégial, les cotes R, en moyennes cumulatives exprimées en pourcentage. Cette moyenne est utilisée depuis 2003 par les universités québécoises participant au
Denis Savard, Serge Sévigny
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
WHAT KIND OF UNIVERSITY RANKING SYSTEM WE NEED
Высшее образование в России, 2022 Taking recent international university ranking trends into account, an analysis of requirements to a ranking system for Russian higher educational institutions was conducted.
Maria V. Seroshtan, Boris M. Vladimirsky
doaj
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
University Ranking: A Study of Criteria
, 2008 A study on çUniversity Ranking: A Study of Criteriaé sponsored by the Association ofPrivate Higher Education Institutions of Thailand (APHEIT) was conducted to: 1) examinethe forms/methods and criteria used by six organizations in five countries in ...
Foopanichpruk, Praedau +1 more
core +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source