Results 51 to 60 of about 1,348,891 (290)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Wikipedia ranking of world universities [PDF]
The European Physical Journal B, 2016 13 pages, 17 figures, 7 tables. Accepted for publication in Eur. Phys. J. B. Supporting information is available at http://perso.utinam.cnrs.fr/~lages/datasets/WRWU/
Lages, J. +2 more
openaire +4 more sources
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
WHEN RANKINGS BECOME THE GOAL: ANALYSIS OF GOODHART'S LAW IN THE RANKING OF UNIVERSITIES IN VIETNAM
Tạp chí Khoa họcGoodhart's Law describes the phenomenon where a measure becomes a target, leading to behaviors aimed at optimizing that measure rather than achieving the true underlying goals.
Nguyen Phuc Quan
doaj +1 more source
WHAT KIND OF UNIVERSITY RANKING SYSTEM WE NEED
Высшее образование в России, 2022 Taking recent international university ranking trends into account, an analysis of requirements to a ranking system for Russian higher educational institutions was conducted.
Maria V. Seroshtan, Boris M. Vladimirsky
doaj
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Mesure et Évaluation en Éducation, 2007 Le présent article décrit les fondements de la formule de conversion des cotes de rendement au collégial, les cotes R, en moyennes cumulatives exprimées en pourcentage. Cette moyenne est utilisée depuis 2003 par les universités québécoises participant au
Denis Savard, Serge Sévigny
doaj +1 more source
UPM ranking 16 dunia UI-GreenMetric World University Ranking 2013 [PDF]
, 2013 SERDANG - Universiti Putra Malaysia (UPM) berjaya meningkatkan ranking penarafan UI-GreenMetric World University Ranking 2013 ke tempat 16 berbanding 19 pada tahun sebelumnya baru-baru ini.
Universiti Putra Malaysia, Bahagian Komunikasi Korporat
core
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source