Results 101 to 110 of about 391,712 (285)

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Perfil das universidades brasileiras de e com potencial de classe mundial

open access: yesAvaliação: Revista da Avaliação da Educação Superior
Resumo: O texto tem por objetivo analisar o perfil das universidades brasileiras que estão na condição de Universidade de Classe Mundial (UCM) e as com potencial para atingir essa condição. O estudo é documental com características exploratórias.
Luiz Alberto Pilatti   +1 more
doaj   +1 more source

Entering the top 100 world university rankings [PDF]

open access: yes, 2014
В 2013 году Томский политехнический университет (ТПУ) одержал победу в конкурсе Министерства образования и науки Российской Федерации на предоставление государственной поддержки ведущим университетам страны в их продвижении втоп-100 лучших вузов мира ...
Чубик, Петр Савельевич
core  

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Can College Rankings Be Believed?

open access: yesShe Ji: The Journal of Design, Economics and Innovation
The article summarizes literature on college and university rankings worldwide and the strategies used by various ranking organizations, including those of government and popular media.
Meredith Davis
doaj   +1 more source

The University of Glasgow at ImageClefPhoto 2009 [PDF]

open access: yes, 2009
In this paper we describe the approaches adopted to generate the five runs submitted to ImageClefPhoto 2009 by the University of Glasgow. The aim of our methods is to exploit document diversity in the rankings. All our runs used text statistics extracted
Goyal, A.   +5 more
core   +3 more sources

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

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