Results 61 to 70 of about 20,422 (254)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Exploring the Potential of Yemeni Universities for Rankings: An Analytical Study of Prominent International University Ranking Systems

open access: yesمجلة العلوم الهندسية والتقنية
Specifically targeting Yemeni universities, this research focuses on their potential to enter and enhance their positions in the international rankings such as Academic Ranking of World Universities (ARWU), Times Higher Education World ...
Fuaad Hasan Abdulrazzak   +8 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

OS RANKINGS ACADÊMICOS INTERNACIONAIS: GÊNESE E RELEVÂNCIA [PDF]

open access: yes, 2013
O presente artigo pretende oferecer um quadro compreensivo do recente fenômeno do sistema de classificação de universidades iniciado na China e que invade e mobiliza os círculos acadêmicos internacionais na primeira década do século XXI. Nos últimos anos,
Laus, Sonia Pereira, Magro, Dalva
core  

Los rankings globales de universidades y su función disciplinaria

open access: yesRevista del Museo de La Plata, 2017
En la última década los rankings de universidades se han transformado en una fuerza importante con gran influencia en las políticas universitarias locales y globales.
Jorge Víctor Crisci   +1 more
doaj   +1 more source

University Structural Units Rankings: Models and Solutions

open access: yesВысшее образование в России, 2020
Formation of strategic management tools in Russian universities, including mechanisms for ranking the activities of structural units is an important task of the innovative development of universities.The article discusses the rating models of structural ...
L. V. Konstantinova
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Institutional responses to university rankings: A tale of adaptation and cognitive framing

open access: yes, 2021
In this chapter we take the opportunity to observe the response of Italian universities to two successive waves of research assessments, culminating into national rankings. We observe the differences in media coverage obtained by the universities between
Belingheri P.   +3 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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