Results 71 to 80 of about 394,522 (288)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

The resilience of rankings in the neoliberal academy

open access: yesTransformation in Higher Education
The multi-billion-dollar university rankings industry purports to offer insights into the quality of institutions, but the extent to which it does so has consistently been refuted.
Sioux McKenna
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

University rankings – a guide to choose a university? [PDF]

open access: yes
In a more and more global world, universities compete for both students and faculty staff. Do university rankings offer a good perspective when it comes to choosing a university, as a student or university professor/researcher?
Dumitru, Ionut, Jianu (Dumitru), Ionela
core   +1 more source

Building an ivory tower in the age of globalization? The process of construction hierarchical academic order in contemporary education through international university rankings [PDF]

open access: yes
University rankings during last decade became extremely popular and “fashionable” topic for general discussions and also for academic researches. As Hazelkorn mentioned in her recently published book (2011), “there is a growing obsession with university ...
Курбатов, Сергій
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

University Rankings: Analysis of Indicators

open access: yesRevista Sociedade, Contabilidade e Gestão, 2015
The worldwide university rankings rank universities based on a set of indicators. However, each ranking system makes use of criteria and metrics of measurement defined according the purpose for which it was created. Thus, this paper aims to identify the
Sandra Mara Iesbik Valmorbida   +2 more
doaj  

2014 Rankings: Key Findings Report [PDF]

open access: yes, 2014
The County Health Rankings & Roadmaps program helps communities identify and implement solutions that make it easier for people to be healthy in their schools, workplaces, and neighborhoods.
Amanda Jovaag   +3 more
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

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