Results 91 to 100 of about 516,921 (318)

A Toolkit for Targeted Neuromodulation of Striatal Direct Pathway Neurons Rescues Parkinsonian Motor Deficits in Mice

Advanced Science, EarlyView.
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong, Yujing Zhang, Junjiao Zhang, Hanhe Liu, Qiwei Liu, Yanglei Li, Lixin Yang, Lixia Li, Zhongjie Liu, Zhen Yuan, Zhonghua Lu, Yefei Chen, Yuantao Li, Yuwu Jiang, Taian Liu   +14 more
wiley   +1 more source

Greater Boston Youth Symphony Orchestras Spring Concert, May 8, 1994 [PDF]

, 1994
This is the concert program of the Greater Boston Youth Symphony Orchestras Spring Concert on Sunday, May 8, 1994 at 4:00 p.m., at the Tsai Performance Ceenter, 685 Commonwealth Avenue. Works performed were Sinfonia KV. 137 "Salzburg Divertimento No.
School of Music, Boston University
core  

Disruption of Treg Homeostasis in Rheumatoid Arthritis via Ferroptosis‐Mediated ETC Collapse and TXK‐STAT3/PLCγ1 Activation

Advanced Science, EarlyView.
In rheumatoid arthritis, synovial Tregs accumulate but are functionally impaired due to iron overload‐induced ferroptosis. This triggers mitochondrial dysfunction and TXK tyrosine kinase‐mediated signaling, leading to Treg destabilization and inflammation.
Jingrong Chen, Xiao Guan, Kexu Xiong, Xiaoyi Shi, Luyao Wu, Chuanxin Su, Jun Zhao, Rongzhen Liang, Huimin Wang, Junlong Dang, Ye Chen, Yiding Xiong, Chi Zhou, Futao Zhao, Zhenhang Zhu, Xiaoli Fan, Li Zhou, Nancy Olsen, Yutong Jiang, Song Guo Zheng   +19 more
wiley   +1 more source

Ascribed and perceived belongning among immigrant youth

, 2016
Drawing on extensive fieldwork in a multicultural urban environment, the paper address the question of belonging among immigrant youth. In an earlier part of the study, a narrative of the categories "Us" (Swedes) and "Them" (Immigrants) revealed negative
Harju, Anne, Piltz, Åse
core  

A Bioinspired Three‐Dimensional High‐Curvature Nano‐Interface Integrated Microfluidic Chip for Small Extracellular Vesicles Enrichment and Machine Learning‐Assisted Prostate Cancer Precision Diagnosis

Advanced Science, EarlyView.
A biotin‐modified artificial insertion peptide functionalized three‐dimensional high‐curvature‐TiO2 nano‐interface was engineered in a microfluidic chip to improve the isolation efficiency of small extracellular vesicles (sEVs). This chip balanced affinity, releasability, and extendibility, enabling high‐throughput recovery of sEVs for downstream ...
Le Wang, Yizhong Liang, Manan Sulaiman, Jiaqi Du, Ming Jiang, Zhihua Wang, Xu Yu, Li Xu   +7 more
wiley   +1 more source

برنامج مقترح من منظور الممارسة العامة في الخدمة الاجتماعية لتنمية وعي الشباب الجامعي بمعايير البيئة الخضراء. [PDF]

مجلة مستقبل العلوم الإجتماعیة
إستهدف البحث تحديد معايير البيئة الخضراء من وجهة نظر الشباب الجامعي، وتحديد دور الاخصائي الاجتماعي كممارس عام  في توعية الطلاب بمعايير البيئة الخضراء لديهم، تحديد الصعوبات التي تواجه دور الاخصائي الاجتماعي كممارس عام في توعية الطلاب بمعايير البيئة ...
صفاء فضل هاشم شحاته
doaj   +1 more source

Suburban Youth Symphony Orchestra

, 1997
Program for the November 15, 1997 performance by the Suburban Youth Symphony Orchestra at Governors State University\u27s Center for Performing Arts.https://opus.govst.edu/cpa_memorabilia/1193/thumbnail ...
Suburban Youth Symphony Orchestra
core  

Cuproptosis and Mitophagy Mediated by the THUMPD1/IGF2R‐Dependent Suppression of AKT and Activation of AMPK Signaling Suppress Lung Adenocarcinoma Progression

Advanced Science, EarlyView.
THUMPD1 drives a tumor‐suppressive signaling cascade in lung adenocarcinoma by promoting IGF2R expression. IGF2R associates with PPP2R1A to suppress AKT and activate AMPK, leading to SLC31A1 upregulation and copper accumulation. Elevated copper disrupts mitochondrial metabolism and induces excessive mitophagy, thereby restraining tumor growth and ...
Kai Wu, Bo Qin, Zhuoyu Gu, Weizheng Ding, Xiaoming Chen, Kaishang Zhang, Yujin Qiao, Shuang Yuan, Song Zhao, Xiangnan Li, Peng Zhang   +10 more
wiley   +1 more source

أدوار الأخصائى الاجتماعى كممارس عام في التخفيف من حدة التنمر السيبراني لدى الشباب الجامعي [PDF]

مجلة مستقبل العلوم الإجتماعیة
الملخص: إستهدف البحث تحديد صور التنمر السيبراني لدى الشباب الجامعي، تحديد الأنشطة والبرامج المقدمة للشباب الجامعي للتخفيف من حدة التنمر السيبراني، تحديد أدوار الأخصائي الاجتماعي كممارس عام للتخفيف من حدة التنمر السيبراني، تحديد المعوقات التي تواجه ...
شيماء كامل يوسف
doaj   +1 more source

Wavy‐Interlocked Stretchable Triboelectric Nanogenerators Enhanced by Liquid Metal Microflowers for Self‐Powered Wearable Motion Monitoring

Advanced Science, EarlyView.
Schematic showing a stretchable triboelectric nanogenerator based on interlocked wavy architectures that uses EGaIn microflower‐embedded PVDF‐TrFE and Nylon‐6 nanofiber membranes. The multi‐petaled, electron‐rich EGaIn microflowers enhance interfacial polarization and capacitance, while the interlocked wavy architecture enlarges the effective contact ...
Qianqian Xu, Huimin Li, Hanmin Zeng, Yahui Meng, Yimeng He, Xinke Hu, Senfeng Zhao, Jianxun Zhang, Peiqiong Zhou, Kechao Zhou, Dou Zhang, Chris Bowen, Yan Zhang   +12 more
wiley   +1 more source