Results 101 to 110 of about 516,921 (318)

Cancer‐Associated Fibroblasts Promote Tumor Immunosuppression in Hepatocellular Carcinoma via the NNMT‐ANGPTL4 Axis

Advanced Science, EarlyView.
ABSTRACT Background & Aims: Cancer‐associated fibroblasts (CAFs) drive immunosuppression in hepatocellular carcinoma (HCC). However, their metabolic regulation remains poorly defined. We investigated the role of nicotinamide N‐methyltransferase (NNMT) in CAFs. Approach & Results: High NNMT expression in CAF tissues was confirmed by western blotting and
Shounan Lu, Shanjia Ke, Hongjun Yu, Zhanzhi Meng, Miaoyu Bai, Yanan Xu, Hui Zhu, Jinwen Yang, Baolin Qian, Bing Yin, Chaoqun Wang, Zhigang Feng, Zhongyu Li, Yongzhi Zhou, Zihao Li, Xinglong Li, Yongliang Hua, Yao Fu, Wei Tang, Yaohua Wu, Yong Ma   +20 more
wiley   +1 more source

Universal Pharmacare and Contraceptive Dispensations Among Youth

JAMA Pediatrics
ImportancePrevious studies have suggested that removing financial barriers to contraception could help reduce unintended pregnancy.ObjectiveTo assess whether introduction of universal public funding for prescription contraception in Ontario (OHIP+) for individuals younger than 25 years and the amended program, which limited public funding to those ...
Downey, Amanda K., Hanna, Steven E., Levine, Mitchell A., Schummers, Laura, Guindon, G. Emmanuel   +4 more
openaire   +2 more sources

Journal Articles -- Trans Youth and Mental Health

, 2016
This archival publication may not reflect current scientific knowledge or recommendations. Current information available from the University of Minnesota Extension: www.extension.umn.edu.Children, Youth, and Family Consortium. (2016). Journal Articles --
Children, Youth, and Family Consortium
core  

Targeting Supramolecular Active Complexes of Nav1.7/Nav1.8 to Relieve Chronic Neuropathic Pain

Advanced Science, EarlyView.
In mice and patients with severe chronic neuropathic pain (NP), Nav1.7, Nav1.8, TrkB, and five cytoskeletal proteins form supramolecular active complexes (SMACs) with polygonal lattice structures as noxious signal amplifiers in dorsal root ganglion (DRG) neurons.
Liting Sun, Hang Xian, Yunxin Shi, Taotan Yang, Hongyan Shuai, Wenchao Hu, Siying Fei, Miao Xu, Taoyuan Yang, Ruilong Xia, Ting Wen, Fengting Zhu, Yan Fu, Yang Li, Wei Xia, Ran Qian, Yuanying Liu, Zhicheng Tian, Lamei Li, Qian Zhou, Lize Xiong, Rui Cong, Ceng Luo, Shengxi Wu, Xiafeng Shen, Xin Yu, Rou‐Gang Xie, Changgeng Peng   +27 more
wiley   +1 more source

Racially motivated offending and targeted interventions

, 2010
The exploratory research presented in this report was commissioned by the YJB and conducted by the Applied Criminology Centre at the University of Huddersfield.
Wiclox, Aiden, Wilcox, Aidan, Wong, Kevin, Smithson, Hannah, Christmann, Kris, Christmann, K., Youth Justice Board, Monchuk, Leanne   +7 more
core  

Dual‐Physical‐Field Nanocatalysis: Injectable Hydrogel Enables Piezo‐Photothermal Synergy for Breast Cancer Therapy

Advanced Science, EarlyView.
ABSTRACT Piezocatalytic therapy (PCT) harnesses mechanical energy to generate tumor‐lethal reactive oxygen species (ROS), but its efficacy is limited by rapid electron‐hole recombination and poor intratumoral retention. To overcome these limitations, we engineered heterostructured BiOCl@CuO nanosheets embedded in an injectable, conductive ...
Can Tian, Shihan Xiao, Xuan Chen, Danni Zhang, Zizhen Liu, Jing Wang, Ning Xie, Wei Li   +7 more
wiley   +1 more source

Utah State University Youth Conservatory Spring Graduation

, 2017
An event for all the participants in the Utah State University Youth Conservatory to perform piano pieces that they practiced and mastered in the months prior.
Utah State University Youth Conservatory, Hirst, Brooke, Weber, Camille, Prettyman, Lizzy, Wilczynski, Ewa, MaLouf, Lauren, Seegmiller, Ethan, Ezola, Emily   +7 more
core  

The Development and Pilot Clinical Study of CD147 Targeted Antagonistic Peptide Probe for Tumor Imaging

Advanced Science, EarlyView.
This study establishes [68Ga]Ga‐DOTA‐AP9 as a first‐in‐human CD147‐targeted PET tracer with favorable safety and specific tumor uptake. Tracer accumulation correlates with CD147 expression in patients, enabling noninvasive quantification of CD147‐positive malignancies.
Xiaokun Ma, Rui Guo, Dongfeng Niu, Yufei Song, Zhenyao Zhang, Xiangxi Meng, Lili Mao, Haifeng Huang, Hua Zhu, Zhi Yang, Teli Liu   +10 more
wiley   +1 more source

FGL2‐HDAC11 Drives Immunothrombosis via NETs‐Mediated Endothelial Capillarization in MASLD Fibrosis

Advanced Science, EarlyView.
ABSTRACT Metabolic dysfunction–associated steatotic liver disease (MASLD) is frequently accompanied by hepatic fibrosis and systemic cardiovascular complications; however, the mechanistic interplay between coagulation abnormalities and disease progression remains poorly defined.
Xitang Li, Junjian Hu, Suping Hai, Peng Hu, Wenhui Wu, Qiang Gao, Binghui Yu, Feiyang Xu, Xizhe Zheng, Qianting Guan, Huiling Xiang, Dong Xi, Weiming Yan, Peng Wang, Bin‐hao Zhang, Qin Ning, Xiaojing Wang   +16 more
wiley   +1 more source

Youth University Subculture as an Element of the Organizational Culture of the University

Педагогика и просвещение
This study, the purpose of which is to identify the views of students of Ulyanovsk State University on the concept of "organizational culture", is based on general scientific methods, such as analysis and synthesis of information from open sources, analytical generalization of theoretical data, and the survey method.
Anastasiya Dmitrievna Gemranova, Tat'yana Sergeevna Mitina, Irina Dmitrievna Mitina   +2 more
openaire   +1 more source