Results 151 to 160 of about 6,759,956 (334)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Using nonverbal sensitivity and cognitive style to discriminate between self and others’ prosocial behavior

Sfera Politicii, 2012
Using dictator game, we evaluated participants (N = 80 students) social value orientations and found that prosocial orientation was shared by the majority of the participants.
Loredana Ivan
doaj  

Discerning the impact of ctDNA detection on patient decision-making in early-stage breast cancer

npj Breast Cancer
The impact of knowledge of circulating tumor DNA (ctDNA) status on patient decisions in high-risk triple-negative breast cancer (TNBC) weighing benefit and toxicity is unknown.
Tarah J. Ballinger, Mary Lou Smith, Elda Railey, Greg Zimet, Bryan P. Schneider   +4 more
doaj   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Asynchronous Implementation of Failure Detectors with partial connectivity and unknown participants

, 2011
L'informatique répartie intègre de plus en plus des réseaux sans fil dynamiques et auto-organisant. Les détecteurs de fautes non fiables sont un mécanisme classique fournissant des informations sur les processus défaillants. Ils peuvent être particulièrement utiles pour gérer le dynamisme important de ces réseaux.
Greve, Fabiola, Sens, Pierre, Arantes, Luciana, Martin, Véronique   +3 more
openaire   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

PERCEPTIONS OF GENETICALLY MODIFIED AND ORGANIC FOODS AND PROCESSES: NORTH DAKOTA COLLEGE STUDENTS [PDF]

Perceptions of genetically modified (GM) and organic food among North Dakota college students were elicited and compared. Participants responded to one of two survey instruments containing identical wording except for reference to genetic modification or
Anderson, Jon C., Lesch, William C., Wachenheim, Cheryl J.   +2 more
core   +1 more source

A neural basis for percept stabilization binocular rivalry [PDF]

, 2008
When the same visual input has conflicting interpretations, conscious perception can alternate spontaneously between each competing percept. Surprisingly, such bistable perception can be stabilized by intermittent stimulus removal, suggesting the ...
Rees, G, Sterzer, P
core  

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source